TY - JOUR
T1 - Path-length-resolved optical Doppler perfusion monitoring
AU - Varghese, Babu
AU - Rajan, Vinayakrishnan
AU - van Leeuwen, Ton G.
AU - Steenbergen, Wiendelt
PY - 2007
Y1 - 2007
N2 - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor
AB - We report the first path-length-resolved perfusion measurements on human skin measured with a phase-modulated low-coherence Mach-Zehnder interferometer with spatially separated fibers for illumination and detection. Optical path lengths of Doppler shifted and unshifted light and path-length-dependent Doppler broadening of multiply scattered light from skin are measured from the Doppler broadened interference peaks appearing in the power spectrum. Perfusion and its variations during occlusion are measured in real time for a given optical path length, and the results are compared with the perfusion signal obtained with a conventional laser Doppler perfusion monitor
U2 - https://doi.org/10.1117/1.2823141
DO - https://doi.org/10.1117/1.2823141
M3 - Article
C2 - 18163803
SN - 1083-3668
VL - 12
SP - 060508
JO - Journal of biomedical optics
JF - Journal of biomedical optics
IS - 6
ER -