Physical activity and white matter lesion progression: Assessment using MRI

L. J. Podewils, E. Guallar, N. Beauchamp, C. G. Lyketsos, L. H. Kuller, P. Scheltens

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)


We evaluated the association between physical activity and changes in white matter lesions (WMLs) on MRI in a sample of 179 older adults comprising 59 incident cases of Alzheimer disease, 60 persons with mild cognitive impairment, and 60 persons who remained cognitively stable over a median 5-year follow-up. Physical activity was not significantly associated with a decreased rate of periventricular or deep WML progression.

Original languageEnglish
Pages (from-to)1223-1226
Number of pages4
Issue number15
Publication statusPublished - 1 Apr 2007

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