Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay.

MG Revello, D. Lilleri, M. Zavattoni, M. Furione, J.M. Middeldorp, G. Gerna

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)


Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

Original languageEnglish
Pages (from-to)1772-4
Number of pages3
JournalJournal of Clinical Microbiology
Issue number4
Publication statusPublished - Apr 2003


  • Amniotic Fluid
  • Cytomegalovirus
  • Cytomegalovirus Infections
  • Evaluation Studies
  • Female
  • Fetal Diseases
  • Humans
  • Journal Article
  • Predictive Value of Tests
  • Pregnancy
  • Prenatal Diagnosis
  • Research Support, Non-U.S. Gov't
  • Self-Sustained Sequence Replication
  • Sensitivity and Specificity

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