Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay.

MG Revello; D. Lilleri; M. Zavattoni; M. Furione; J.M. Middeldorp; G. Gerna

doi:https://doi.org/10.1128/JCM.41.4.1772-1774.2003

Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay.

MG Revello, D. Lilleri, M. Zavattoni, M. Furione, J.M. Middeldorp, G. Gerna

Research output: Contribution to journal › Article › Academic › peer-review

27 Citations (Scopus)

Abstract

Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

Original language	English
Pages (from-to)	1772-4
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	41
Issue number	4
DOIs	https://doi.org/10.1128/JCM.41.4.1772-1774.2003
Publication status	Published - Apr 2003

Keywords

Amniotic Fluid
Cytomegalovirus
Cytomegalovirus Infections
Evaluation Studies
Female
Fetal Diseases
Humans
Journal Article
Predictive Value of Tests
Pregnancy
Prenatal Diagnosis
Research Support, Non-U.S. Gov't
Self-Sustained Sequence Replication
Sensitivity and Specificity

Access to Document

https://doi.org/10.1128/JCM.41.4.1772-1774.2003

https://research.vumc.nl/ws/files/9999932/PMC153931

Cite this

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title = "Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay.",

abstract = "Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.",

keywords = "Amniotic Fluid, Cytomegalovirus, Cytomegalovirus Infections, Evaluation Studies, Female, Fetal Diseases, Humans, Journal Article, Predictive Value of Tests, Pregnancy, Prenatal Diagnosis, Research Support, Non-U.S. Gov't, Self-Sustained Sequence Replication, Sensitivity and Specificity",

author = "MG Revello and D. Lilleri and M. Zavattoni and M. Furione and J.M. Middeldorp and G. Gerna",

year = "2003",

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language = "English",

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TY - JOUR

T1 - Prenatal diagnosis of congenital human cytomegalovirus infection in amniotic fluid by nucleic acid sequence-based amplification assay.

AU - Revello, MG

AU - Lilleri, D.

AU - Zavattoni, M.

AU - Furione, M.

AU - Middeldorp, J.M.

AU - Gerna, G.

PY - 2003/4

Y1 - 2003/4

N2 - Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

AB - Nucleic acid sequence-based amplification assays for detection of human cytomegalovirus (HCMV) immediate-early and pp67 mRNA in 65 amniotic fluid samples tested for prenatal diagnosis of congenital HCMV infection showed sensitivity, specificity, and negative and positive predictive values >90%.

KW - Amniotic Fluid

KW - Cytomegalovirus

KW - Cytomegalovirus Infections

KW - Evaluation Studies

KW - Female

KW - Fetal Diseases

KW - Humans

KW - Journal Article

KW - Predictive Value of Tests

KW - Pregnancy

KW - Prenatal Diagnosis

KW - Research Support, Non-U.S. Gov't

KW - Self-Sustained Sequence Replication

KW - Sensitivity and Specificity

U2 - https://doi.org/10.1128/JCM.41.4.1772-1774.2003

DO - https://doi.org/10.1128/JCM.41.4.1772-1774.2003

M3 - Article

C2 - 12682184

SN - 0095-1137

VL - 41

SP - 1772

EP - 1774

JO - Journal of Clinical Microbiology

JF - Journal of Clinical Microbiology

IS - 4

ER -