Propofol extravasation in a breast cancer patient

E J M Huijbers, J W Baars, P F E Schutte, J H M Schellens, J H Beijnen

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A breast cancer patient experienced an accidental propofol extravasation in the dorsum of her hand during a Port-A-Cath replacement. She had heavy pain which was treated with analgesics. The patient's hand was cooled and kept in an upright position. Three days later the patient received her last AC (adriamycin/cyclophosphamide) course without complications. Propofol extravasation did not result in tissue necrosis in this case. AC chemotherapy could be administered safely 3 days after propofol extravasation.

Original languageEnglish
Pages (from-to)195-8
Number of pages4
JournalJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
Issue number4
Publication statusPublished - Dec 2008


  • Adult
  • Anesthetics, Intravenous/administration & dosage
  • Breast Neoplasms/complications
  • Cyclophosphamide/therapeutic use
  • Doxorubicin/therapeutic use
  • Extravasation of Diagnostic and Therapeutic Materials/etiology
  • Female
  • Humans
  • Propofol/administration & dosage

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