TY - JOUR
T1 - Quantification of Feto-fetal Transfusion Rate through a Single Placental Arterio-venous Anastomosis in a Monochorionic Twin Pregnancy
AU - Lopriore, E.
AU - van den Wijngaard, J. P. H. M.
AU - Pasman, S. A.
AU - Oepkes, D.
AU - Walther, F. J.
AU - van Gemert, M. J. C.
AU - Vandenbussche, F. P. H. A.
PY - 2009
Y1 - 2009
N2 - Twin-to-twin transfusion syndrome (TTTS) is due to unbalanced inter-twin blood flow through placental vascular anastomoses. We present a TTTS-case treated with fetoscopic laser surgery that allowed us to calculate the net inter-twin blood flow. In the weeks following laser treatment, the ex-recipient developed severe fetal anemia and was treated with two intrauterine adult red cell transfusions (at 26 and 29 weeks' gestation, respectively). After birth, placental injection with color-latex identified a single residual arterio-venous anastomosis from the ex-recipient to the ex-donor. We measured the fetal and adult hemoglobin concentrations in the anemic fetus before and after both intrauterine transfusions, and in both twins at birth. On the basis of these measurements, we calculated the blood flow across the residual arterio-venous anastomosis and found it to be 5.8 +/- 1.5 mL/24 h after the 1st transfusion and 11.4 +/- 2.9 mL/24 h after the 2nd transfusion. (C) 2008 Elsevier Ltd. All rights reserved
AB - Twin-to-twin transfusion syndrome (TTTS) is due to unbalanced inter-twin blood flow through placental vascular anastomoses. We present a TTTS-case treated with fetoscopic laser surgery that allowed us to calculate the net inter-twin blood flow. In the weeks following laser treatment, the ex-recipient developed severe fetal anemia and was treated with two intrauterine adult red cell transfusions (at 26 and 29 weeks' gestation, respectively). After birth, placental injection with color-latex identified a single residual arterio-venous anastomosis from the ex-recipient to the ex-donor. We measured the fetal and adult hemoglobin concentrations in the anemic fetus before and after both intrauterine transfusions, and in both twins at birth. On the basis of these measurements, we calculated the blood flow across the residual arterio-venous anastomosis and found it to be 5.8 +/- 1.5 mL/24 h after the 1st transfusion and 11.4 +/- 2.9 mL/24 h after the 2nd transfusion. (C) 2008 Elsevier Ltd. All rights reserved
U2 - https://doi.org/10.1016/j.placenta.2008.11.012
DO - https://doi.org/10.1016/j.placenta.2008.11.012
M3 - Article
C2 - 19108886
SN - 0143-4004
VL - 30
SP - 223
EP - 225
JO - Placenta
JF - Placenta
IS - 3
ER -