Rapid screening by real-time 16S rDNA PCR for bacterial contamination of blood products

Hendrik W. Reesink, Tamimount Mohammadi, Rubyn N. I. Pietersz, Paul H. M. Savelkoul

Research output: Contribution to journalReview articleAcademicpeer-review

7 Citations (Scopus)


Although blood component transfusion is currently regarded as safe, adverse events may occur in recipients of these products. Among those, blood borne viral, bacterial and parasitic infections are best known. For detection of bacterial contamination in platelet concentrates various methods are available or under investigation. One of these methods, real-time polymerase chain reaction (PCR) with particular focus on real-time 16S rDNA detection, will be discussed in this review
Original languageEnglish
Pages (from-to)954-962
JournalClinical chemistry and laboratory medicine
Issue number7
Publication statusPublished - 2008

Cite this