TY - JOUR
T1 - Rapid screening by real-time 16S rDNA PCR for bacterial contamination of blood products
AU - Reesink, Hendrik W.
AU - Mohammadi, Tamimount
AU - Pietersz, Rubyn N. I.
AU - Savelkoul, Paul H. M.
PY - 2008
Y1 - 2008
N2 - Although blood component transfusion is currently regarded as safe, adverse events may occur in recipients of these products. Among those, blood borne viral, bacterial and parasitic infections are best known. For detection of bacterial contamination in platelet concentrates various methods are available or under investigation. One of these methods, real-time polymerase chain reaction (PCR) with particular focus on real-time 16S rDNA detection, will be discussed in this review
AB - Although blood component transfusion is currently regarded as safe, adverse events may occur in recipients of these products. Among those, blood borne viral, bacterial and parasitic infections are best known. For detection of bacterial contamination in platelet concentrates various methods are available or under investigation. One of these methods, real-time polymerase chain reaction (PCR) with particular focus on real-time 16S rDNA detection, will be discussed in this review
U2 - https://doi.org/10.1515/CCLM.2008.155
DO - https://doi.org/10.1515/CCLM.2008.155
M3 - Review article
C2 - 18605948
SN - 1434-6621
VL - 46
SP - 954
EP - 962
JO - Clinical chemistry and laboratory medicine
JF - Clinical chemistry and laboratory medicine
IS - 7
ER -