Recent updates on incubation of drug craving: A mini-review

Xuan Li, Daniele Caprioli, Nathan J. Marchant

Research output: Contribution to journalReview articleAcademicpeer-review

67 Citations (Scopus)

Abstract

Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural mechanisms contributing to incubation of drug craving. In this mini-review, we first discuss three excellent Addiction Biology publications on incubation of drug craving in both human and laboratory animals. We then review several key publications from the past year on behavioral and mechanistic findings related to incubation of drug craving. Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural mechanisms contributing to incubation of drug craving. Here, we first discuss three excellent Addiction Biology publications on incubation of drug craving in both human and laboratory animals. We then review several key publications from the past year on behavioral and mechanistic findings related to incubation of drug craving.

Original languageEnglish
Pages (from-to)872-876
Number of pages5
JournalAddiction Biology
Volume20
Issue number5
DOIs
Publication statusPublished - 1 Sept 2015

Keywords

  • Addiction
  • cocaine
  • dopamine
  • glutamate
  • incubation
  • relapse

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