Repetitive endoscopic sinus surgery failure: a role for radical surgery?

Ward J. M. Videler, Volkert B. Wreesmann, Freerk W. van der Meulen, Paul P. Knegt, Wytske J. Fokkens

Research output: Contribution to JournalArticleAcademicpeer-review

25 Citations (Scopus)


OBJECTIVES: Endoscopic sinus surgery (ESS) is considered to be the golden standard for surgery in patients with chronic rhinosinusitis and nasal polyposis. However, there is still a small group of patients unresponsive despite repetitive surgery. Radical surgery aimed at reduction of the inflammatory burden and optimization of drainage of the sinuses has been suggested as a last resort for these patients. STUDY DESIGN: A prospective, questionnaire-based study was conducted in a group of 23 patients who underwent Denker's procedure for refractory chronic rhinosinusitis. Symptoms were evaluated before Denker's procedure and 12 months and 2 years after surgery. RESULTS: Patients reported improvement of feelings of congestion in 74%, rhinorrhea in 70%, and nasal obstruction in 60% of the cases. The following postoperative improvements were statistically significant: rhinorrhea (P = 0.001), feelings of congestion (P = 0.02), and nasal obstruction (P = 0.03). Reduced olfactory perception and asthma did not improve. CONCLUSION: Radical surgery may be a viable treatment option in case of recurrent ESS failure. EBM rating: C-4
Original languageEnglish
Pages (from-to)586-591
JournalOtolaryngology-head and neck surgery
Issue number4
Publication statusPublished - 2006

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