Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Steven A. Muller; Helen L. Leavis; Karim Taha; Leo Koenderman; Steven A. J. Chamuleau; Willem J. L. Suyker; Maarten J. Cramer

doi:https://doi.org/10.1016/j.jaccas.2021.07.034

Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Steven A. Muller, Helen L. Leavis, Karim Taha, Leo Koenderman, Steven A. J. Chamuleau, Willem J. L. Suyker, Maarten J. Cramer

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.)

Original language	English
Pages (from-to)	1483-1488
Journal	JACC: Case Reports
Volume	3
Issue number	13
DOIs	https://doi.org/10.1016/j.jaccas.2021.07.034
Publication status	Published - 6 Oct 2021

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title = "Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements",

abstract = "We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.)",

author = "Muller, {Steven A.} and Leavis, {Helen L.} and Karim Taha and Leo Koenderman and Chamuleau, {Steven A. J.} and Suyker, {Willem J. L.} and Cramer, {Maarten J.}",

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AU - Muller, Steven A.

AU - Leavis, Helen L.

AU - Taha, Karim

AU - Koenderman, Leo

AU - Chamuleau, Steven A. J.

AU - Suyker, Willem J. L.

AU - Cramer, Maarten J.

PY - 2021/10/6

Y1 - 2021/10/6

N2 - We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.)

AB - We present a young patient who had to undergo 5 mitral valve replacements (MVR) because of a repetitive immune-mediated noninfectious endocarditis. The patient was treated with multiple anti-inflammatory drugs and high-dose prednisone. After the fifth MVR, the patient remained in stable condition using Anakinra after 22 months of follow-up. (Level of Difficulty: Advanced.)

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85122741910&origin=inward

UR - https://www.ncbi.nlm.nih.gov/pubmed/34693347

U2 - https://doi.org/10.1016/j.jaccas.2021.07.034

DO - https://doi.org/10.1016/j.jaccas.2021.07.034

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JO - JACC: Case Reports

JF - JACC: Case Reports

IS - 13

ER -

Repetitive Immune-Mediated Noninfectious Endocarditis Necessitating 5 Mitral Valve Replacements

Abstract

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