TY - JOUR
T1 - Reverse-engineering the serrated neoplasia pathway using CRISPR–Cas9
AU - Bleijenberg, Arne
AU - Dekker, Evelien
PY - 2018
Y1 - 2018
N2 - Serrated polyps contribute substantially to the development of colorectal cancer. Unfortunately, our knowledge of the molecular events that drive these lesions is limited. Now, a new study describes an organoid-based mouse model that might accelerate our understanding of the serrated neoplasia pathway.
AB - Serrated polyps contribute substantially to the development of colorectal cancer. Unfortunately, our knowledge of the molecular events that drive these lesions is limited. Now, a new study describes an organoid-based mouse model that might accelerate our understanding of the serrated neoplasia pathway.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85048123899&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/29875470
U2 - https://doi.org/10.1038/s41575-018-0035-4
DO - https://doi.org/10.1038/s41575-018-0035-4
M3 - Article
C2 - 29875470
SN - 1759-5045
VL - 15
SP - 522
EP - 524
JO - Nature reviews. Gastroenterology & hepatology
JF - Nature reviews. Gastroenterology & hepatology
IS - 9
ER -