TY - JOUR
T1 - Risk of cutaneous squamous cell carcinoma due to occupational exposure to solar ultraviolet radiation
T2 - Protocol for a systematic review and meta-analysis
AU - Paulo, Marília Silva
AU - Symanzik, Cara
AU - Ádam, Balázs
AU - Gobba, Fabriziomaria
AU - Kezic, Sanja
AU - van der Molen, Henk F.
AU - Peters, Cheryl E.
AU - Rocholl, Marc
AU - Tenkate, Thomas
AU - John, Swen Malte
AU - Loney, Tom
AU - Modenese, Alberto
AU - Wittlich, Marc
N1 - Publisher Copyright: © 2023 Paulo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2023/3/1
Y1 - 2023/3/1
N2 - Solar ultraviolet radiation (UVR) is the most significant occupational carcinogenic exposure in terms of the number of workers exposed (i.e., outdoor workers). Consequently, solar UVR-induced skin cancers are among the most common forms of occupational malignancies that are potentially expected globally. This systematic review is registered in PROSPERO (CRD42021295221) and aims to assess the risk of cutaneous squamous cell carcinoma (cSCC) associated to occupational solar UVR exposure. Systematic searches will be performed in three electronic literature databases (PubMed/Medline, EMBASE, and Scopus). Further references will be retrieved by a manual search (e.g., in grey literature databases, internet search engines, and organizational websites). We will include cohort studies and case-control studies. Risk of Bias assessment will be conducted separately for case-control and cohort studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) will be used for the certainty of assessment. In case quantitative pooling is not feasible, a narrative synthesis of results will be performed.
AB - Solar ultraviolet radiation (UVR) is the most significant occupational carcinogenic exposure in terms of the number of workers exposed (i.e., outdoor workers). Consequently, solar UVR-induced skin cancers are among the most common forms of occupational malignancies that are potentially expected globally. This systematic review is registered in PROSPERO (CRD42021295221) and aims to assess the risk of cutaneous squamous cell carcinoma (cSCC) associated to occupational solar UVR exposure. Systematic searches will be performed in three electronic literature databases (PubMed/Medline, EMBASE, and Scopus). Further references will be retrieved by a manual search (e.g., in grey literature databases, internet search engines, and organizational websites). We will include cohort studies and case-control studies. Risk of Bias assessment will be conducted separately for case-control and cohort studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) will be used for the certainty of assessment. In case quantitative pooling is not feasible, a narrative synthesis of results will be performed.
UR - http://www.scopus.com/inward/record.url?scp=85149316488&partnerID=8YFLogxK
U2 - https://doi.org/10.1371/journal.pone.0282664
DO - https://doi.org/10.1371/journal.pone.0282664
M3 - Review article
C2 - 36867594
SN - 1932-6203
VL - 18
JO - PLOS ONE
JF - PLOS ONE
IS - 3 March
M1 - e0282664
ER -