Selective phosphorylation of PKA targets after beta-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model

Aref Najafi; Vasco Sequeira Oliveira; Michiel Helmes; Ilse A. E. Bollen; Max Goebel; Jessica A. Regan; Lucie Carrier; Diederik W. D. Kuster; Jolanda Van der Velden

doi:https://doi.org/10.1093/cvr/cvw026

Selective phosphorylation of PKA targets after beta-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model

Aref Najafi, Vasco Sequeira Oliveira, Michiel Helmes, Ilse A. E. Bollen, Max Goebel, Jessica A. Regan, Lucie Carrier, Diederik W. D. Kuster, Jolanda Van der Velden

Physiology (VUmc)

Research output: Contribution to journal › Article › Academic › peer-review

21 Citations (Scopus)

Original language	English
Pages (from-to)	200-214
Journal	Cardiovascular research
Volume	110
Issue number	2
DOIs	https://doi.org/10.1093/cvr/cvw026
Publication status	Published - 15 May 2016

Keywords

Calcium handling
Contractility
Hypertrophic cardiomyopathy
beta-adrenergic signalling

Access to Document

https://doi.org/10.1093/cvr/cvw026

Cite this

Najafi, A., Sequeira Oliveira, V., Helmes, M., Bollen, I. A. E., Goebel, M., Regan, J. A., Carrier, L., Kuster, D. W. D., & Van der Velden, J. (2016). Selective phosphorylation of PKA targets after beta-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model. Cardiovascular research, 110(2), 200-214. https://doi.org/10.1093/cvr/cvw026

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AU - Sequeira Oliveira, Vasco

AU - Helmes, Michiel

AU - Bollen, Ilse A. E.

AU - Goebel, Max

AU - Regan, Jessica A.

AU - Carrier, Lucie

AU - Kuster, Diederik W. D.

AU - Van der Velden, Jolanda

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KW - Calcium handling

KW - Contractility

KW - Hypertrophic cardiomyopathy

KW - beta-adrenergic signalling

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SP - 200

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