Should we aim at tissue renin-angiotensin systems?

J. F. Smits, R. C. Passier, M. J. Daemen

Research output: Contribution to journalReview articleAcademicpeer-review

6 Citations (Scopus)

Abstract

Recent developments in our knowledge of the renin-angiotensin system (RAS) necessitate an update of the classical view on this system. These developments pertain to the pathways leading to formation of angiotensin II and other active metabolites, their receptors, biological functions and the presence of renin-angiotensin systems in tissues. The implications of the above new developments for the current interest in tissue renin-angiotensin systems as potential targets for drug therapy in cardiovascular disease are discussed in this review
Original languageEnglish
Pages (from-to)93-99
JournalPharmacy World & Science
Volume20
Issue number3
DOIs
Publication statusPublished - 1998

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