TY - JOUR
T1 - Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index
AU - Aalbers, Caroline J.
AU - Gerlag, Danielle M.
AU - Vervoordeldonk, Margriet J.
AU - Tak, Paul P.
AU - Landewé, Robert B.
PY - 2015
Y1 - 2015
N2 - To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97). This study supports the use of the CCI as a single-joint assessment after single-joint intervention. NTR-1210
AB - To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97). This study supports the use of the CCI as a single-joint assessment after single-joint intervention. NTR-1210
U2 - https://doi.org/10.3899/jrheum.140956
DO - https://doi.org/10.3899/jrheum.140956
M3 - Article
C2 - 26178282
SN - 0315-162X
VL - 42
SP - 1672
EP - 1676
JO - Journal of rheumatology
JF - Journal of rheumatology
IS - 9
ER -