Spatial correlation of trace elements with morphological features of atherosclerotic plaques

R. B. Roijers; R. K. Dutta; P. H.A. Mutsaers; M. J.J. Gijbels; M. P.J. De Winther; J. J.M. De Goeij; G. J. Van Der Vusse

doi:https://doi.org/10.1016/j.nimb.2005.01.064

Spatial correlation of trace elements with morphological features of atherosclerotic plaques

R. B. Roijers, R. K. Dutta, P. H.A. Mutsaers, M. J.J. Gijbels, M. P.J. De Winther, J. J.M. De Goeij, G. J. Van Der Vusse

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy.

Original language	English
Pages (from-to)	239-244
Number of pages	6
Journal	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
Volume	231
Issue number	1-4
DOIs	https://doi.org/10.1016/j.nimb.2005.01.064
Publication status	Published - Apr 2005
Event	Nuclear Microprobe Technology and Applications Proceedings of the 9th International Conference on Nuclear Microprobe Technology and ICNMTA 2004 - Duration: 13 Sept 2004 → 17 Sept 2004

Keywords

Atherosclerosis
Histology
Nuclear microprobe
PIXE
Region of interest

Access to Document

https://doi.org/10.1016/j.nimb.2005.01.064

Cite this

Roijers, R. B., Dutta, R. K., Mutsaers, P. H. A., Gijbels, M. J. J., De Winther, M. P. J., De Goeij, J. J. M., & Van Der Vusse, G. J. (2005). Spatial correlation of trace elements with morphological features of atherosclerotic plaques. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, 231(1-4), 239-244. https://doi.org/10.1016/j.nimb.2005.01.064

@article{0efe7c8e02064a5a89ad8ed02e807675,

title = "Spatial correlation of trace elements with morphological features of atherosclerotic plaques",

abstract = "A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy.",

keywords = "Atherosclerosis, Histology, Nuclear microprobe, PIXE, Region of interest",

author = "Roijers, {R. B.} and Dutta, {R. K.} and Mutsaers, {P. H.A.} and Gijbels, {M. J.J.} and {De Winther}, {M. P.J.} and {De Goeij}, {J. J.M.} and {Van Der Vusse}, {G. J.}",

note = "Funding Information: This research work is funded by FOM (Project number 00PMT13). The authors{\textquoteright} thank{\textquoteright}s go to Paul Bomans, Hans Duimel and Peter Frederik for their assistance in sample preparation.; Nuclear Microprobe Technology and Applications Proceedings of the 9th International Conference on Nuclear Microprobe Technology and ICNMTA 2004 ; Conference date: 13-09-2004 Through 17-09-2004",

year = "2005",

month = apr,

doi = "https://doi.org/10.1016/j.nimb.2005.01.064",

language = "English",

volume = "231",

pages = "239--244",

journal = "Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms",

issn = "0168-583X",

publisher = "Elsevier",

number = "1-4",

}

Roijers, RB, Dutta, RK, Mutsaers, PHA, Gijbels, MJJ , De Winther, MPJ, De Goeij, JJM & Van Der Vusse, GJ 2005, 'Spatial correlation of trace elements with morphological features of atherosclerotic plaques', Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, vol. 231, no. 1-4, pp. 239-244. https://doi.org/10.1016/j.nimb.2005.01.064

Spatial correlation of trace elements with morphological features of atherosclerotic plaques. / Roijers, R. B.; Dutta, R. K.; Mutsaers, P. H.A. et al.
In: Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms, Vol. 231, No. 1-4, 04.2005, p. 239-244.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Spatial correlation of trace elements with morphological features of atherosclerotic plaques

AU - Roijers, R. B.

AU - Dutta, R. K.

AU - Mutsaers, P. H.A.

AU - Gijbels, M. J.J.

AU - De Winther, M. P.J.

AU - De Goeij, J. J.M.

AU - Van Der Vusse, G. J.

N1 - Funding Information: This research work is funded by FOM (Project number 00PMT13). The authors’ thank’s go to Paul Bomans, Hans Duimel and Peter Frederik for their assistance in sample preparation.

PY - 2005/4

Y1 - 2005/4

N2 - A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy.

AB - A method is presented to correlate spatially trace elements with morphological features of atherosclerotic plaques by combining microprobe techniques and histological staining. Patterns from scanning transmission ion microscopy and morphology obtained from optical microscopy could be brought in fair to good agreement. It was possible to obtain element concentrations belonging to specific morphological features as indicated by optical microscopy.

KW - Atherosclerosis

KW - Histology

KW - Nuclear microprobe

KW - PIXE

KW - Region of interest

UR - http://www.scopus.com/inward/record.url?scp=33644506468&partnerID=8YFLogxK

U2 - https://doi.org/10.1016/j.nimb.2005.01.064

DO - https://doi.org/10.1016/j.nimb.2005.01.064

M3 - Article

SN - 0168-583X

VL - 231

SP - 239

EP - 244

JO - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

JF - Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

IS - 1-4

T2 - Nuclear Microprobe Technology and Applications Proceedings of the 9th International Conference on Nuclear Microprobe Technology and ICNMTA 2004

Y2 - 13 September 2004 through 17 September 2004

ER -

Spatial correlation of trace elements with morphological features of atherosclerotic plaques

Abstract

Keywords

Access to Document

Other files and links

Cite this