TY - JOUR
T1 - Stereotactic Arrhythmia Radioablation (STAR)
T2 - Assessment of cardiac and respiratory heart motion in ventricular tachycardia patients - A STOPSTORM.eu consortium review
AU - Stevens, Raoul R.F.
AU - Hazelaar, Colien
AU - Fast, Martin F.
AU - Mandija, Stefano
AU - Grehn, Melanie
AU - Cvek, Jakub
AU - Knybel, Lukas
AU - Dvorak, Pavel
AU - Pruvot, Etienne
AU - Verhoeff, Joost J.C.
AU - Blanck, Oliver
AU - van Elmpt, Wouter
N1 - Funding Information: In addition, Lukas Knybel and Jakub Cvek declare having received funding from the Ministry of Health of the Czech Republic under grant project AZV NU20-02-00244 . Otherwise, the authors of this manuscript have nothing to declare. Funding Information: The authors would like to thank all members of the STOPSTORM consortium (see https://stopstorm.eu/en/consortium). This study is part of the project “Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) Consortium", that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 945119. Funding Information: The authors would like to thank all members of the STOPSTORM consortium (see https://stopstorm.eu/en/consortium). This study is part of the project “Standardized Treatment and Outcome Platform for Stereotactic Therapy Of Re-entrant tachycardia by a Multidisciplinary (STOPSTORM) Consortium", that has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. 945119. In addition, Lukas Knybel and Jakub Cvek declare having received funding from the Ministry of Health of the Czech Republic under grant project AZV NU20-02-00244. Otherwise, the authors of this manuscript have nothing to declare. Publisher Copyright: © 2023 The Authors
PY - 2023/11/1
Y1 - 2023/11/1
N2 - Aim: To identify the optimal STereotactic Arrhythmia Radioablation (STAR) strategy for individual patients, cardiorespiratory motion of the target volume in combination with different treatment methodologies needs to be evaluated. However, an authoritative overview of the amount of cardiorespiratory motion in ventricular tachycardia (VT) patients is missing. Methods: In this STOPSTORM consortium study, we performed a literature review to gain insight into cardiorespiratory motion of target volumes for STAR. Motion data and target volumes were extracted and summarized. Results: Out of the 232 studies screened, 56 provided data on cardiorespiratory motion, of which 8 provided motion amplitudes in VT patients (n = 94) and 10 described (cardiac/cardiorespiratory) internal target volumes (ITVs) obtained in VT patients (n = 59). Average cardiac motion of target volumes was < 5 mm in all directions, with maximum values of 8.0, 5.2 and 6.5 mm in Superior-Inferior (SI), Left-Right (LR), Anterior-Posterior (AP) direction, respectively. Cardiorespiratory motion of cardiac (sub)structures showed average motion between 5–8 mm in the SI direction, whereas, LR and AP motions were comparable to the cardiac motion of the target volumes. Cardiorespiratory ITVs were on average 120–284% of the gross target volume. Healthy subjects showed average cardiorespiratory motion of 10–17 mm in SI and 2.4–7 mm in the AP direction. Conclusion: This review suggests that despite growing numbers of patients being treated, detailed data on cardiorespiratory motion for STAR is still limited. Moreover, data comparison between studies is difficult due to inconsistency in parameters reported. Cardiorespiratory motion is highly patient-specific even under motion-compensation techniques. Therefore, individual motion management strategies during imaging, planning, and treatment for STAR are highly recommended.
AB - Aim: To identify the optimal STereotactic Arrhythmia Radioablation (STAR) strategy for individual patients, cardiorespiratory motion of the target volume in combination with different treatment methodologies needs to be evaluated. However, an authoritative overview of the amount of cardiorespiratory motion in ventricular tachycardia (VT) patients is missing. Methods: In this STOPSTORM consortium study, we performed a literature review to gain insight into cardiorespiratory motion of target volumes for STAR. Motion data and target volumes were extracted and summarized. Results: Out of the 232 studies screened, 56 provided data on cardiorespiratory motion, of which 8 provided motion amplitudes in VT patients (n = 94) and 10 described (cardiac/cardiorespiratory) internal target volumes (ITVs) obtained in VT patients (n = 59). Average cardiac motion of target volumes was < 5 mm in all directions, with maximum values of 8.0, 5.2 and 6.5 mm in Superior-Inferior (SI), Left-Right (LR), Anterior-Posterior (AP) direction, respectively. Cardiorespiratory motion of cardiac (sub)structures showed average motion between 5–8 mm in the SI direction, whereas, LR and AP motions were comparable to the cardiac motion of the target volumes. Cardiorespiratory ITVs were on average 120–284% of the gross target volume. Healthy subjects showed average cardiorespiratory motion of 10–17 mm in SI and 2.4–7 mm in the AP direction. Conclusion: This review suggests that despite growing numbers of patients being treated, detailed data on cardiorespiratory motion for STAR is still limited. Moreover, data comparison between studies is difficult due to inconsistency in parameters reported. Cardiorespiratory motion is highly patient-specific even under motion-compensation techniques. Therefore, individual motion management strategies during imaging, planning, and treatment for STAR are highly recommended.
KW - Cardiac SBRT
KW - Cardiac radioablation
KW - Stereotactic Arrhythmia Radioablation
KW - Ventricular tachycardia
UR - http://www.scopus.com/inward/record.url?scp=85169057015&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/j.radonc.2023.109844
DO - https://doi.org/10.1016/j.radonc.2023.109844
M3 - Article
C2 - 37543057
SN - 0167-8140
VL - 188
JO - Radiotherapy and oncology
JF - Radiotherapy and oncology
M1 - 109844
ER -