Sympathetic nervous system function in HIV-associated adipose redistribution syndrome

Petra J. van Gurp; Cees J. Tack; Marc van der Valk; Peter Reiss; Jacques W. M. Lenders; Fred C. G. J. Sweep; Hans P. Sauerwein

doi:https://doi.org/10.1097/01.aids.0000216379.91936.84

Sympathetic nervous system function in HIV-associated adipose redistribution syndrome

Petra J. van Gurp, Cees J. Tack, Marc van der Valk, Peter Reiss, Jacques W. M. Lenders, Fred C. G. J. Sweep, Hans P. Sauerwein

Research output: Contribution to journal › Editorial › Academic › peer-review

13 Citations (Scopus)

Abstract

It was recently suggested that HIV-associated adipose redistribution syndrome (HARS) results from an autonomic dysbalance. We investigated the local and global sympathetic nervous system function of patients with HIV-1 infection and HARS. Interstitial noradrenaline concentrations in skeletal muscle and subcutaneous adipose tissue were increased in the absence of changes in global sympathetic nerve activity, consistent with locally increased sympathetic activity. This could promote localized lipolysis in subcutaneous adipose tissue and contribute to the development of HARS

Original language	English
Pages (from-to)	773-775
Journal	AIDS (London, England)
Volume	20
Issue number	5
DOIs	https://doi.org/10.1097/01.aids.0000216379.91936.84
Publication status	Published - 2006

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https://doi.org/10.1097/01.aids.0000216379.91936.84

Cite this

@article{cfc7ac0341a74aa3a964ce88d59e74dd,

title = "Sympathetic nervous system function in HIV-associated adipose redistribution syndrome",

abstract = "It was recently suggested that HIV-associated adipose redistribution syndrome (HARS) results from an autonomic dysbalance. We investigated the local and global sympathetic nervous system function of patients with HIV-1 infection and HARS. Interstitial noradrenaline concentrations in skeletal muscle and subcutaneous adipose tissue were increased in the absence of changes in global sympathetic nerve activity, consistent with locally increased sympathetic activity. This could promote localized lipolysis in subcutaneous adipose tissue and contribute to the development of HARS",

author = "{van Gurp}, {Petra J.} and Tack, {Cees J.} and {van der Valk}, Marc and Peter Reiss and Lenders, {Jacques W. M.} and Sweep, {Fred C. G. J.} and Sauerwein, {Hans P.}",

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language = "English",

volume = "20",

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T1 - Sympathetic nervous system function in HIV-associated adipose redistribution syndrome

AU - van Gurp, Petra J.

AU - Tack, Cees J.

AU - van der Valk, Marc

AU - Reiss, Peter

AU - Lenders, Jacques W. M.

AU - Sweep, Fred C. G. J.

AU - Sauerwein, Hans P.

PY - 2006

Y1 - 2006

N2 - It was recently suggested that HIV-associated adipose redistribution syndrome (HARS) results from an autonomic dysbalance. We investigated the local and global sympathetic nervous system function of patients with HIV-1 infection and HARS. Interstitial noradrenaline concentrations in skeletal muscle and subcutaneous adipose tissue were increased in the absence of changes in global sympathetic nerve activity, consistent with locally increased sympathetic activity. This could promote localized lipolysis in subcutaneous adipose tissue and contribute to the development of HARS

AB - It was recently suggested that HIV-associated adipose redistribution syndrome (HARS) results from an autonomic dysbalance. We investigated the local and global sympathetic nervous system function of patients with HIV-1 infection and HARS. Interstitial noradrenaline concentrations in skeletal muscle and subcutaneous adipose tissue were increased in the absence of changes in global sympathetic nerve activity, consistent with locally increased sympathetic activity. This could promote localized lipolysis in subcutaneous adipose tissue and contribute to the development of HARS

U2 - https://doi.org/10.1097/01.aids.0000216379.91936.84

DO - https://doi.org/10.1097/01.aids.0000216379.91936.84

M3 - Editorial

C2 - 16514309

SN - 0269-9370

VL - 20

SP - 773

EP - 775

JO - AIDS (London, England)

JF - AIDS (London, England)

IS - 5

ER -