Synaptobrevin, sphingolipids, and secretion: lube 'n' go at the synapse

M. Verhage; G. van Meer

doi:https://doi.org/10.1016/j.neuron.2009.05.019

Synaptobrevin, sphingolipids, and secretion: lube 'n' go at the synapse

M. Verhage, G. van Meer

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

For neurotransmitter release to occur, proteins and lipids have to work together. The classical view of this process is that a variety of proteins work hard to force the unwilling, fusion-aversive lipids into merging. In this issue of Neuron, a study by Darios et al. paints the opposite picture: a lipid metabolite stimulates the reluctant vSNARE synaptobrevin to engage in fusogenic protein complexes. © 2009 Elsevier Inc. All rights reserved.

Original language	English
Pages (from-to)	603-605
Number of pages	2
Journal	Neuron
Volume	62
Issue number	5
DOIs	https://doi.org/10.1016/j.neuron.2009.05.019
Publication status	Published - 2009

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https://doi.org/10.1016/j.neuron.2009.05.019

Cite this

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title = "Synaptobrevin, sphingolipids, and secretion: lube 'n' go at the synapse",

abstract = "For neurotransmitter release to occur, proteins and lipids have to work together. The classical view of this process is that a variety of proteins work hard to force the unwilling, fusion-aversive lipids into merging. In this issue of Neuron, a study by Darios et al. paints the opposite picture: a lipid metabolite stimulates the reluctant vSNARE synaptobrevin to engage in fusogenic protein complexes. {\textcopyright} 2009 Elsevier Inc. All rights reserved.",

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