Tall stature

Sabine E. Hannema, Lars Sävendahl

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review


Although tall stature in itself is not a medical problem, underlying pathology should be ruled out as this may be associated with significant morbidity or even mortality. (Family) history, physical examination and evaluation of the growth chart should focus on signs of a syndromic cause, such as macrocephaly, disproportion, dysmorphic features and intellectual disability, growth acceleration with or without signs of puberty, and on height in relation to parental height. Targeted investigations can be ordered to confirm a suspected diagnosis. Familial tall stature is the most common diagnosis. Treatment is generally not indicated but in exceptionally tall individuals who request treatment epiphysiodesis can be considered to reduce growth. This is more effective than high dose sex steroid treatment. Because of serious long term effects on fertility we recommend against high dose estrogen treatment.

Original languageEnglish
Title of host publicationEncyclopedia of Endocrine Diseases
Number of pages8
ISBN (Electronic)9780128122006
ISBN (Print)9780128121993
Publication statusPublished - 1 Jan 2018


  • Disproportion
  • Dysmorphic features
  • Epiphysiodesis
  • Growth
  • Growth hormone excess
  • Growth reduction
  • High-dose estrogen
  • High-dose testosterone
  • Klinefelter syndrome
  • Macrocephaly
  • Marfan syndrome
  • Precocious puberty
  • Tall stature

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