Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich

Peter de Boer; Agustinus J. A. J. van de Schoot; Henrike Westerveld; Mark Smit; Marrije R. Buist; Arjan Bel; Coen R. N. Rasch; Lukas J. A. Stalpers

doi:https://doi.org/10.1007/s00066-017-1224-8

Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich

Peter de Boer, Agustinus J. A. J. van de Schoot, Henrike Westerveld, Mark Smit, Marrije R. Buist, Arjan Bel, Coen R. N. Rasch, Lukas J. A. Stalpers

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

Abstract

The aim of the study was to investigate the potential clinical benefit from both target tailoring by excluding the tumour-free proximal part of the uterus during image-guided adaptive radiotherapy (IGART) and improved dose conformity based on intensity-modulated proton therapy (IMPT). meanfor bladder, sigmoid, rectum and bowel bag were compared, and the normal tissue complication probability (NTCP) for ≥grade 2 acute small bowel toxicity was calculated. 3, respectively, during standard IGART alone. In patients with cervical cancer, both proton therapy and MRI-based target tailoring lead to a significant reduction in the dose to surrounding organs at risk and small bowel toxicity

Original language	English
Pages (from-to)	255-263
Journal	Strahlentherapie und Onkologie
Volume	194
Issue number	3
Early online date	2017
DOIs	https://doi.org/10.1007/s00066-017-1224-8
Publication status	Published - 2018

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https://doi.org/10.1007/s00066-017-1224-8

Cite this

de Boer, P., van de Schoot, A. J. A. J., Westerveld, H., Smit, M., Buist, M. R., Bel, A., Rasch, C. R. N., & Stalpers, L. J. A. (2018). Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich. Strahlentherapie und Onkologie, 194(3), 255-263. https://doi.org/10.1007/s00066-017-1224-8

de Boer, Peter ; van de Schoot, Agustinus J. A. J. ; Westerveld, Henrike et al. / Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich. In: Strahlentherapie und Onkologie. 2018 ; Vol. 194, No. 3. pp. 255-263.

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title = "Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpr{\"a}zisierung und Protonentherapie zur Reduktion der D{\"u}nndarmdosis bei der Strahlentherapie des Geb{\"a}rmutterhalskrebses : Ein Planvergleich",

abstract = "The aim of the study was to investigate the potential clinical benefit from both target tailoring by excluding the tumour-free proximal part of the uterus during image-guided adaptive radiotherapy (IGART) and improved dose conformity based on intensity-modulated proton therapy (IMPT). meanfor bladder, sigmoid, rectum and bowel bag were compared, and the normal tissue complication probability (NTCP) for ≥grade 2 acute small bowel toxicity was calculated. 3, respectively, during standard IGART alone. In patients with cervical cancer, both proton therapy and MRI-based target tailoring lead to a significant reduction in the dose to surrounding organs at risk and small bowel toxicity",

author = "{de Boer}, Peter and {van de Schoot}, {Agustinus J. A. J.} and Henrike Westerveld and Mark Smit and Buist, {Marrije R.} and Arjan Bel and Rasch, {Coen R. N.} and Stalpers, {Lukas J. A.}",

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language = "English",

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de Boer, P, van de Schoot, AJAJ, Westerveld, H, Smit, M, Buist, MR, Bel, A, Rasch, CRN & Stalpers, LJA 2018, 'Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich', Strahlentherapie und Onkologie, vol. 194, no. 3, pp. 255-263. https://doi.org/10.1007/s00066-017-1224-8

Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich. / de Boer, Peter; van de Schoot, Agustinus J. A. J.; Westerveld, Henrike et al.
In: Strahlentherapie und Onkologie, Vol. 194, No. 3, 2018, p. 255-263.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

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AB - The aim of the study was to investigate the potential clinical benefit from both target tailoring by excluding the tumour-free proximal part of the uterus during image-guided adaptive radiotherapy (IGART) and improved dose conformity based on intensity-modulated proton therapy (IMPT). meanfor bladder, sigmoid, rectum and bowel bag were compared, and the normal tissue complication probability (NTCP) for ≥grade 2 acute small bowel toxicity was calculated. 3, respectively, during standard IGART alone. In patients with cervical cancer, both proton therapy and MRI-based target tailoring lead to a significant reduction in the dose to surrounding organs at risk and small bowel toxicity

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de Boer P, van de Schoot AJAJ, Westerveld H, Smit M, Buist MR, Bel A et al. Target tailoring and proton beam therapy to reduce small bowel dose in cervical cancer radiotherapy : A comparison of benefits Zielvolumenpräzisierung und Protonentherapie zur Reduktion der Dünndarmdosis bei der Strahlentherapie des Gebärmutterhalskrebses : Ein Planvergleich. Strahlentherapie und Onkologie. 2018;194(3):255-263. Epub 2017. doi: https://doi.org/10.1007/s00066-017-1224-8