TY - JOUR
T1 - The accuracy of prenatal ultrasound in determining the type of orofacial cleft
AU - Loozen, C. S.
AU - Maarse, W.
AU - Manten, G. T. R.
AU - Pistorius, L.
AU - Breugem, C. C.
PY - 2015
Y1 - 2015
N2 - Objective: The aim of this study was to assess the accuracy of prenatal transabdominal ultrasound in determining the oral cleft type. Methods: A retrospective cohort study was performed on all consecutive cases of orofacial cleft diagnosed by prenatal ultrasound examination in the Wilhelmina Children's Hospital, a tertiary referral hospital, between January 2002 and December 2012. Prenatal findings were compared with postnatal diagnoses. Results: A total of 134 patients were included. The mean gestational age at ultrasound examination was 24weeks+5days. Prenatal diagnosis was in accordance with postnatal findings in 76.9% of the cases (103/134) with regard to the cleft type. Underestimation of the cleft occurred in 19.4% (26/134), whereas in 3.7% (5/134), the extent was overestimated. In distinguishing bilateral from unilateral clefts, no errors were made. Conclusion: Prenatal ultrasound is accurate in assessing the types of orofacial clefts in a large majority of the cases and is completely accurate in distinguishing between unilateral and bilateral clefts. This study indicates that it is a reliable technique to assess the cleft type, which is important for counseling future parents. Although, the clinician should be aware of the fact that a cleft palate is easily missed, and subsequently, underestimation of cleft extend is frequent.
AB - Objective: The aim of this study was to assess the accuracy of prenatal transabdominal ultrasound in determining the oral cleft type. Methods: A retrospective cohort study was performed on all consecutive cases of orofacial cleft diagnosed by prenatal ultrasound examination in the Wilhelmina Children's Hospital, a tertiary referral hospital, between January 2002 and December 2012. Prenatal findings were compared with postnatal diagnoses. Results: A total of 134 patients were included. The mean gestational age at ultrasound examination was 24weeks+5days. Prenatal diagnosis was in accordance with postnatal findings in 76.9% of the cases (103/134) with regard to the cleft type. Underestimation of the cleft occurred in 19.4% (26/134), whereas in 3.7% (5/134), the extent was overestimated. In distinguishing bilateral from unilateral clefts, no errors were made. Conclusion: Prenatal ultrasound is accurate in assessing the types of orofacial clefts in a large majority of the cases and is completely accurate in distinguishing between unilateral and bilateral clefts. This study indicates that it is a reliable technique to assess the cleft type, which is important for counseling future parents. Although, the clinician should be aware of the fact that a cleft palate is easily missed, and subsequently, underestimation of cleft extend is frequent.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84933672961&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/25721357
U2 - https://doi.org/10.1002/pd.4582
DO - https://doi.org/10.1002/pd.4582
M3 - Article
C2 - 25721357
SN - 0197-3851
VL - 35
SP - 652
EP - 655
JO - Prenatal diagnosis
JF - Prenatal diagnosis
IS - 7
ER -