TY - JOUR
T1 - The characterisation of subjective cognitive decline
AU - Jessen, Frank
AU - Amariglio, Rebecca E.
AU - Buckley, Rachel F.
AU - van der Flier, Wiesje M.
AU - Han, Ying
AU - Molinuevo, José Luis
AU - Rabin, Laura
AU - Rentz, Dorene M.
AU - Rodriguez-Gomez, Octavio
AU - Saykin, Andrew J.
AU - Sikkes, Sietske A.M.
AU - Smart, Colette M.
AU - Wolfsgruber, Steffen
AU - Wagner, Michael
PY - 2020/3/1
Y1 - 2020/3/1
N2 - A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.
AB - A growing awareness about brain health and Alzheimer's disease in the general population is leading to an increasing number of cognitively unimpaired individuals, who are concerned that they have reduced cognitive function, to approach the medical system for help. The term subjective cognitive decline (SCD) was conceived in 2014 to describe this condition. Epidemiological data provide evidence that the risk for mild cognitive impairment and dementia is increased in individuals with SCD. However, the majority of individuals with SCD will not show progressive cognitive decline. An individually tailored diagnostic process might be reasonable to identify or exclude underlying medical conditions in an individual with SCD who actively seeks medical help. An increasing number of studies are investigating the link between SCD and the very early stages of Alzheimer's disease and other neurodegenerative diseases.
UR - http://www.scopus.com/inward/record.url?scp=85079417063&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079417063&partnerID=8YFLogxK
U2 - https://doi.org/10.1016/S1474-4422(19)30368-0
DO - https://doi.org/10.1016/S1474-4422(19)30368-0
M3 - Review article
C2 - 31958406
SN - 1474-4422
VL - 19
SP - 271
EP - 278
JO - The Lancet Neurology
JF - The Lancet Neurology
IS - 3
ER -
