The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency

S. Bulk; J. Berkhof; L. Rozendaal; N. C.Fransen Daalmeijer; M. Gök; F. A. De Schipper; F. J. Van Kemenade; P. J.F. Snijders; C. J.L.M. Meijer

doi:https://doi.org/10.1038/sj.bjc.6603693

The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency

S. Bulk, J. Berkhof, L. Rozendaal, N. C.Fransen Daalmeijer, M. Gök, F. A. De Schipper, F. J. Van Kemenade, P. J.F. Snijders, C. J.L.M. Meijer

Research output: Contribution to journal › Article › Academic › peer-review

21 Citations (Scopus)

Abstract

In one geographical area, 14 high-risk human papillomavirus types in cervical intraepithelial neoplasia (CIN2/3; n=139) and cervical squamous cell carcinoma (SCC; n=84) were analysed. HPV18 was more prevalent in SCC than CIN2/3 (OR 9.8; 95% confidence interval: 2.5-39). Other high-risk types prevalences corresponded in CIN2/3 and SCC. Evaluations using CIN2/3 as a measure of efficiency underestimate the contribution of HPV18 to SCC.

Original language	English
Pages (from-to)	1234-1236
Number of pages	3
Journal	British journal of cancer
Volume	96
Issue number	8
DOIs	https://doi.org/10.1038/sj.bjc.6603693
Publication status	Published - 23 Apr 2007

Keywords

Cervical intraepithelial neoplasia
Epidemiology
Human papillomavirus
PALGA
Squamous cell carcinoma

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https://doi.org/10.1038/sj.bjc.6603693

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title = "The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency",

abstract = "In one geographical area, 14 high-risk human papillomavirus types in cervical intraepithelial neoplasia (CIN2/3; n=139) and cervical squamous cell carcinoma (SCC; n=84) were analysed. HPV18 was more prevalent in SCC than CIN2/3 (OR 9.8; 95% confidence interval: 2.5-39). Other high-risk types prevalences corresponded in CIN2/3 and SCC. Evaluations using CIN2/3 as a measure of efficiency underestimate the contribution of HPV18 to SCC.",

keywords = "Cervical intraepithelial neoplasia, Epidemiology, Human papillomavirus, PALGA, Squamous cell carcinoma",

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T1 - The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency

AU - Bulk, S.

AU - Berkhof, J.

AU - Rozendaal, L.

AU - Daalmeijer, N. C.Fransen

AU - Gök, M.

AU - De Schipper, F. A.

AU - Van Kemenade, F. J.

AU - Snijders, P. J.F.

AU - Meijer, C. J.L.M.

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AB - In one geographical area, 14 high-risk human papillomavirus types in cervical intraepithelial neoplasia (CIN2/3; n=139) and cervical squamous cell carcinoma (SCC; n=84) were analysed. HPV18 was more prevalent in SCC than CIN2/3 (OR 9.8; 95% confidence interval: 2.5-39). Other high-risk types prevalences corresponded in CIN2/3 and SCC. Evaluations using CIN2/3 as a measure of efficiency underestimate the contribution of HPV18 to SCC.

KW - Cervical intraepithelial neoplasia

KW - Epidemiology

KW - Human papillomavirus

KW - PALGA

KW - Squamous cell carcinoma

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The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency

Abstract

Keywords

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