The effects of a graded activity intervention for low back pain in occupational health on sick leave, functional status and pain: 12-month results of a randomized controlled trial: 12-month results of a randomized controlled trial

H. Hlobil, J.B. Staal, J.W.R. Twisk, A. Koke, G.A.M. Ariens, T. Smid, W. van Mechelen, Albere Köke

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Introduction: Behaviorally oriented graded activity interventions have been suggested for sick-listed workers with low back pain on return to work, but have not been extensively evaluated. Methods: One hundred and thirty-four workers were randomly assigned to either a graded activity intervention (n = 67) or usual care (n = 67) and followed-up for 12 months. Results: The graded activity group returned back to work faster with a median of 54 days compared to 67 days in the usual care group. The graded activity intervention was more effective after approximately 50 days post-randomization (HRR = 1.9, CI = 1.2-3.1, p = 0.01). Differences between the groups in number of recurrent episodes, total number of days of sick leave due to low back pain, and total number of days of sick leave due to all diagnoses, were in favor of the graded activity group, although not statistically significant. No effects of the graded activity intervention were found for functional status or pain. Conclusion: Graded activity intervention is a valuable strategy to enhance short-term return to work outcomes. © 2005 Springer Science + Business Media, Inc.
Original languageEnglish
Pages (from-to)569-580
Number of pages12
JournalJournal of Occupational Rehabilitation
Issue number4
Publication statusPublished - Dec 2005


  • Activities of Daily Living
  • Exercise
  • Humans
  • Low Back Pain/rehabilitation
  • Multivariate Analysis
  • Netherlands
  • Occupational Diseases/rehabilitation
  • Proportional Hazards Models
  • Recurrence
  • Sick Leave/statistics & numerical data
  • Single-Blind Method
  • Survival Analysis

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