TY - JOUR
T1 - The epidemiology of renal replacement therapy in two different parts of the world
T2 - the Latin American Dialysis and Transplant Registry versus the European Renal Association-European Dialysis and Transplant Association Registry
AU - Collaborators
AU - Luxardo, Rosario
AU - Kramer, Anneke
AU - González-Bedat, Maria Carlota
AU - Massy, Ziad A
AU - Jager, Kitty J
AU - Rosa-Diez, Guillermo
AU - Noordzij, Marlies
N1 - Funding Information: This paper was written by Rosario Luxardo et al. as part of the 2015-2016 ERA-EDTA/SLANH Registries fellowship. The ERAEDTA Registry is funded by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and is an official body of the ERA-EDTA. We would like to thank the patients and staff of all the dialysis and transplant units that have contributed data via their national and subnational renal registries. In addition, we would like to thank all persons and organizations that have contributed to the work of the RLADTR and ERA-EDTA registries. Funding Information: paper was written by Rosario Luxardo et al. as part of the 2015–2016 ERA-EDTA/ SLANH Registries fellowship. The ERA-EDTA Registry is funded by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and is an official body of the ERA-EDTA. We would like to thank the patients and staff of all the dialysis and transplant units that have contributed data via their national and subnational renal registries. In addition, we would like to thank all persons and organizations that have contributed to the work of the RLADTR and ERA-EDTA registries. Publisher Copyright: © 2018 Pan American Health Organization. All rights reserved.
PY - 2018
Y1 - 2018
N2 - Objective: To compare the epidemiology of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in Latin America and Europe, as well as to study differences in macroeconomic indicators, demographic and clinical patient characteristics, mortality rates, and causes of death between these two populations.Methods: We used data from 20 Latin American and 49 European national and subnational renal registries that had provided data to the Latin American Dialysis and Renal Transplant Registry (RLADTR) and the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, respectively. The incidence and prevalence of RRT in 2013 were calculated per million population (pmp), overall and by subcategories of age, sex, primary renal disease, and treatment modality. The correlation between gross domestic product and the prevalence of RRT was analyzed using linear regression. Trends in the prevalence of RRT between 2004 and 2013 were assessed using Joinpoint regression analysis.Results: In 2013, the overall incidence at day 91 after the onset of RRT was 181 pmp for Latin American countries and 130 pmp for European countries. The overall prevalence was 660 pmp for Latin America and 782 pmp for Europe. In the Latin American countries, the annual increase in the prevalence averaged 4.0% (95% confidence interval (CI): 2.5%-5.6%) from 2004 to 2013, while the European countries showed an average annual increase of 2.2% (95% CI: 2.0%-2.4%) for the same time period. The crude mortality rate was higher in Latin America than in Europe (112 versus 100 deaths per 1 000 patient-years), and cardiovascular disease was the main cause of death in both of those regions.Conclusions: There are considerable differences between Latin America and Europe in the epidemiology of RRT for ESRD. Further research is needed to explore the reasons for these differences.
AB - Objective: To compare the epidemiology of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in Latin America and Europe, as well as to study differences in macroeconomic indicators, demographic and clinical patient characteristics, mortality rates, and causes of death between these two populations.Methods: We used data from 20 Latin American and 49 European national and subnational renal registries that had provided data to the Latin American Dialysis and Renal Transplant Registry (RLADTR) and the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry, respectively. The incidence and prevalence of RRT in 2013 were calculated per million population (pmp), overall and by subcategories of age, sex, primary renal disease, and treatment modality. The correlation between gross domestic product and the prevalence of RRT was analyzed using linear regression. Trends in the prevalence of RRT between 2004 and 2013 were assessed using Joinpoint regression analysis.Results: In 2013, the overall incidence at day 91 after the onset of RRT was 181 pmp for Latin American countries and 130 pmp for European countries. The overall prevalence was 660 pmp for Latin America and 782 pmp for Europe. In the Latin American countries, the annual increase in the prevalence averaged 4.0% (95% confidence interval (CI): 2.5%-5.6%) from 2004 to 2013, while the European countries showed an average annual increase of 2.2% (95% CI: 2.0%-2.4%) for the same time period. The crude mortality rate was higher in Latin America than in Europe (112 versus 100 deaths per 1 000 patient-years), and cardiovascular disease was the main cause of death in both of those regions.Conclusions: There are considerable differences between Latin America and Europe in the epidemiology of RRT for ESRD. Further research is needed to explore the reasons for these differences.
KW - Chronic
KW - Dialysis
KW - Europe
KW - Kidney failure
KW - Kidney transplantation
KW - Latin America
KW - Mortality
KW - Renal replacement therapy
UR - http://www.scopus.com/inward/record.url?scp=85073766177&partnerID=8YFLogxK
U2 - https://doi.org/10.26633/RPSP.2018.87
DO - https://doi.org/10.26633/RPSP.2018.87
M3 - Article
C2 - 31093115
SN - 1020-4989
VL - 42
SP - e87
JO - Revista panamericana de salud publica = Pan American journal of public health
JF - Revista panamericana de salud publica = Pan American journal of public health
M1 - e872018
ER -