The hepatocyte growth factor/Met pathway in development, tumorigenesis, and B-cell differentiation

R. van der Voort, T. E. Taher, P. W. Derksen, M. Spaargaren, R. van der Neut, S. T. Pals

Research output: Contribution to journalReview articleAcademicpeer-review

98 Citations (Scopus)

Abstract

This article summarizes the structure, signal transduction and physiologic functions of the HGF/Met pathway, as well as its role in tumor growth, invasion, and metastasis. Moreover, it highlights recent studies indicating a role for the HGF/Met pathway in antigen-specific B-cell development and B-cell neoplasia
Original languageEnglish
Pages (from-to)39-90
JournalAdvances in cancer research
Volume79
DOIs
Publication statusPublished - 2000

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