TY - JOUR
T1 - The incidence of psychotic disorders among migrants and minority ethnic groups in Europe
T2 - findings from the multinational EU-GEI study
AU - Termorshuizen, Fabian
AU - van der Ven, Els
AU - Tarricone, Ilaria
AU - Jongsma, Hannah E
AU - Gayer-Anderson, Charlotte
AU - Lasalvia, Antonio
AU - Tosato, Sarah
AU - Quattrone, Diego
AU - La Cascia, Caterina
AU - Szöke, Andrei
AU - Berardi, Domenico
AU - Llorca, Pierre-Michel
AU - de Haan, Lieuwe
AU - Velthorst, Eva
AU - Bernardo, Miguel
AU - Sanjuán, Julio
AU - Arrojo, Manuel
AU - Murray, Robin M
AU - Rutten, Bart P
AU - Jones, Peter B
AU - van Os, Jim
AU - Kirkbride, James B
AU - Morgan, Craig
AU - Selten, Jean-Paul
PY - 2022/5
Y1 - 2022/5
N2 - BACKGROUND: In Europe, the incidence of psychotic disorder is high in certain migrant and minority ethnic groups (hence: 'minorities'). However, it is unknown how the incidence pattern for these groups varies within this continent. Our objective was to compare, across sites in France, Italy, Spain, the UK and the Netherlands, the incidence rates for minorities and the incidence rate ratios (IRRs, minorities v. the local reference population).METHODS: The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) study was conducted between 2010 and 2015. We analyzed data on incident cases of non-organic psychosis (International Classification of Diseases, 10th edition, codes F20-F33) from 13 sites.RESULTS: The standardized incidence rates for minorities, combined into one category, varied from 12.2 in Valencia to 82.5 per 100 000 in Paris. These rates were generally high at sites with high rates for the reference population, and low at sites with low rates for the reference population. IRRs for minorities (combined into one category) varied from 0.70 (95% CI 0.32-1.53) in Valencia to 2.47 (95% CI 1.66-3.69) in Paris (test for interaction: p = 0.031). At most sites, IRRs were higher for persons from non-Western countries than for those from Western countries, with the highest IRRs for individuals from sub-Saharan Africa (adjusted IRR = 3.23, 95% CI 2.66-3.93).CONCLUSIONS: Incidence rates vary by region of origin, region of destination and their combination. This suggests that they are strongly influenced by the social context.
AB - BACKGROUND: In Europe, the incidence of psychotic disorder is high in certain migrant and minority ethnic groups (hence: 'minorities'). However, it is unknown how the incidence pattern for these groups varies within this continent. Our objective was to compare, across sites in France, Italy, Spain, the UK and the Netherlands, the incidence rates for minorities and the incidence rate ratios (IRRs, minorities v. the local reference population).METHODS: The European Network of National Schizophrenia Networks Studying Gene-Environment Interactions (EU-GEI) study was conducted between 2010 and 2015. We analyzed data on incident cases of non-organic psychosis (International Classification of Diseases, 10th edition, codes F20-F33) from 13 sites.RESULTS: The standardized incidence rates for minorities, combined into one category, varied from 12.2 in Valencia to 82.5 per 100 000 in Paris. These rates were generally high at sites with high rates for the reference population, and low at sites with low rates for the reference population. IRRs for minorities (combined into one category) varied from 0.70 (95% CI 0.32-1.53) in Valencia to 2.47 (95% CI 1.66-3.69) in Paris (test for interaction: p = 0.031). At most sites, IRRs were higher for persons from non-Western countries than for those from Western countries, with the highest IRRs for individuals from sub-Saharan Africa (adjusted IRR = 3.23, 95% CI 2.66-3.93).CONCLUSIONS: Incidence rates vary by region of origin, region of destination and their combination. This suggests that they are strongly influenced by the social context.
KW - Dopamine
KW - epidemiology
KW - ethnicity
KW - migration
KW - psychosis
KW - race
KW - schizophrenia
KW - stress
UR - http://www.scopus.com/inward/record.url?scp=85092233782&partnerID=8YFLogxK
U2 - https://doi.org/10.1017/S0033291720003219
DO - https://doi.org/10.1017/S0033291720003219
M3 - Article
C2 - 32958094
SN - 0033-2917
VL - 52
SP - 1376
EP - 1385
JO - Psychological Medicine
JF - Psychological Medicine
IS - 7
ER -