TY - JOUR
T1 - The potential beneficial role of faecal microbiota transplantation in diseases other than Clostridium difficile infection
AU - Singh, R.
AU - Nieuwdorp, M.
AU - ten Berge, I. J. M.
AU - Bemelman, F. J.
AU - Geerlings, S. E.
PY - 2014
Y1 - 2014
N2 - This review gives an outline of the indications for faecal microbiota transplantation (FMT) for diseases other than Clostridium difficile (C. difficile) infection. The remarkable efficacy of FMT against C. difficile infection has already been demonstrated. The use of FMT for other diseases, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and metabolic syndrome, is now being evaluated. The currently available data suggest that FMT might be beneficial for IBD (including ulcerative colitis and, to some extent, Crohn's disease), IBS, and insulin resistance. Several randomized clinical trials are currently being performed, and data are eagerly awaited. A new field of research for the implementation of FMT is the eradication of pathogenic and multiresistant enteric microorganisms. A few animal studies have been performed within this field, but hardly any research data from human studies are available at present
AB - This review gives an outline of the indications for faecal microbiota transplantation (FMT) for diseases other than Clostridium difficile (C. difficile) infection. The remarkable efficacy of FMT against C. difficile infection has already been demonstrated. The use of FMT for other diseases, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and metabolic syndrome, is now being evaluated. The currently available data suggest that FMT might be beneficial for IBD (including ulcerative colitis and, to some extent, Crohn's disease), IBS, and insulin resistance. Several randomized clinical trials are currently being performed, and data are eagerly awaited. A new field of research for the implementation of FMT is the eradication of pathogenic and multiresistant enteric microorganisms. A few animal studies have been performed within this field, but hardly any research data from human studies are available at present
U2 - https://doi.org/10.1111/1469-0691.12799
DO - https://doi.org/10.1111/1469-0691.12799
M3 - Review article
C2 - 25274035
SN - 1198-743X
VL - 20
SP - 1119
EP - 1125
JO - Clinical Microbiology and Infection
JF - Clinical Microbiology and Infection
IS - 11
ER -