TY - JOUR
T1 - The upper extremity postthrombotic syndrome score
T2 - an international Delphi consensus study to determine the score's functional disability component
AU - Schropp, Ludo
AU - Cats, Roos B.
AU - de Kleijn, Robert J. C. M. F.
AU - van Hattum, Eline S.
AU - Middeldorp, Saskia
AU - Nijkeuter, Mathilde
AU - Westerink, Jan
AU - Petri, Bart-Jeroen
AU - de Borst, Gert J.
AU - in collaboration with the Upper Extremity PTS group
AU - Schropp, L.
AU - Cats, R. B.
AU - de Kleijn, R. J. C. M. F.
AU - Black, S.
AU - Garcia, D.
AU - Meijer, K.
AU - Nijziel, M. R.
AU - Klappe, E. M.
AU - Geroulakos, G.
AU - van Ommen, C. H.
AU - van Rijn, M. J. E.
AU - Freischlag, J.
AU - Kruip, M. J. H. A.
AU - Huisman, M. V.
AU - Coppens, M.
AU - Teijink, J. A. W.
AU - Kakkos, S. K.
AU - le Gal, G.
AU - Westerweel, P. E.
AU - Avila, M. L.
AU - Kreuziger, L. Baumann
AU - Cate-Hoek, A. J. Ten
AU - Lee, A. Y. Y.
AU - Koelemay, M. J.
AU - Srivastava, A.
AU - Hovens, M. M. C.
AU - Ünlü, Cagdas
AU - Klok, F. A.
AU - Douketis, J.
AU - Stansby, G.
AU - Illig, K. A.
AU - Thompson, R. W.
AU - Bax, W. A.
AU - Poli, D.
AU - Kahn, S. R.
AU - van Hattum, E. S.
AU - Middeldorp, S.
AU - Nijkeuter, M.
AU - Westerink, J.
AU - Petri, B. J.
AU - de Borst, G. J.
N1 - Publisher Copyright: © 2023 The Author(s)
PY - 2023/1/1
Y1 - 2023/1/1
N2 - Background: In upper extremity thrombosis research, the occurrence of upper extremity postthrombotic syndrome (UE-PTS) is commonly used as the main outcome parameter. However, there is currently no reporting standard or a validated method to assess UE-PTS presence and severity. In a recent Delphi study, consensus was reached on a preliminary UE-PTS score, combining 5 symptoms, 3 signs, and the inclusion of a functional disability score. However, no consensus was reached on which functional disability score to be included. Objectives: The aim of the current Delphi consensus study was to determine the specific type of functional disability score to finalize UE-PTS score. Methods: This Delphi project was designed as a three-round study using open text questions, statements with 7-point Likert scales, and multiple-choice questions. The CREDES recommendations for Delphi studies were applied. In this context, a systematic review was conducted before the start of the Delphi rounds to identify the available functional disability scores as available in the literature and present these to the expert panel. Results: Thirty-five of 47 initially invited international experts from multiple disciplines completed all the Delphi rounds. In the second round, consensus was reached on the incorporation of the quick disabilities of the arm, shoulder, and hand (QuickDASH) in the UE-PTS score, rendering the third round obsolete. Conclusion: Consensus was reached that the QuickDASH should be incorporated in the UE-PTS score. The UE-PTS score will need to be validated in a large cohort of patients with upper extremity thrombosis before it can be used in clinical practice and future research.
AB - Background: In upper extremity thrombosis research, the occurrence of upper extremity postthrombotic syndrome (UE-PTS) is commonly used as the main outcome parameter. However, there is currently no reporting standard or a validated method to assess UE-PTS presence and severity. In a recent Delphi study, consensus was reached on a preliminary UE-PTS score, combining 5 symptoms, 3 signs, and the inclusion of a functional disability score. However, no consensus was reached on which functional disability score to be included. Objectives: The aim of the current Delphi consensus study was to determine the specific type of functional disability score to finalize UE-PTS score. Methods: This Delphi project was designed as a three-round study using open text questions, statements with 7-point Likert scales, and multiple-choice questions. The CREDES recommendations for Delphi studies were applied. In this context, a systematic review was conducted before the start of the Delphi rounds to identify the available functional disability scores as available in the literature and present these to the expert panel. Results: Thirty-five of 47 initially invited international experts from multiple disciplines completed all the Delphi rounds. In the second round, consensus was reached on the incorporation of the quick disabilities of the arm, shoulder, and hand (QuickDASH) in the UE-PTS score, rendering the third round obsolete. Conclusion: Consensus was reached that the QuickDASH should be incorporated in the UE-PTS score. The UE-PTS score will need to be validated in a large cohort of patients with upper extremity thrombosis before it can be used in clinical practice and future research.
KW - Delphi technique
KW - diagnosis
KW - functional status
KW - postthrombotic syndrome
KW - surveys and questionnaires
KW - thoracic outlet syndrome
KW - upper extremity deep vein thrombosis
UR - http://www.scopus.com/inward/record.url?scp=85147162629&partnerID=8YFLogxK
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85147162629&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/36873563
U2 - https://doi.org/10.1016/j.rpth.2023.100051
DO - https://doi.org/10.1016/j.rpth.2023.100051
M3 - Article
C2 - 36873563
SN - 2475-0379
VL - 7
JO - Research and practice in thrombosis and haemostasis
JF - Research and practice in thrombosis and haemostasis
IS - 1
M1 - 100051
ER -