The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

on behalf of the Executive Committee of the European Society of Human Genetics; the Public and Professional Policy Committee of the European Society of Human Genetics

doi:https://doi.org/10.1038/s41431-021-01000-x

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

on behalf of the Executive Committee of the European Society of Human Genetics, the Public and Professional Policy Committee of the European Society of Human Genetics

Research output: Contribution to journal › Article › Academic › peer-review

35 Citations (Scopus)

Original language	English
Journal	European journal of human genetics
Early online date	2021
DOIs	https://doi.org/10.1038/s41431-021-01000-x
Publication status	E-pub ahead of print - 2021

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https://doi.org/10.1038/s41431-021-01000-x

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on behalf of the Executive Committee of the European Society of Human Genetics, & the Public and Professional Policy Committee of the European Society of Human Genetics (2021). The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice. European journal of human genetics. Advance online publication. https://doi.org/10.1038/s41431-021-01000-x

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title = "The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice",

author = "Francesca Forzano and Olga Antonova and Angus Clarke and {de Wert}, Guido and Sabine Hentze and Yalda Jamshidi and Yves Moreau and Markus Perola and Inga Prokopenko and Andrew Read and Alexandre Reymond and Vigdis Stefansdottir and {van el}, Carla and Maurizio Genuardi and Borut Peterlin and Carla Oliveira and Karin Writzl and Houge, {Gunnar Douzgos} and Christophe Cordier and Heidi Howard and Milan Macek and Melegh, {B. la} and Alvaro Mendes and Dragica Radojkovic and {on behalf of the Executive Committee of the European Society of Human Genetics} and Emmanuelle Rial-Sebbag and {the Public and Professional Policy Committee of the European Society of Human Genetics} and Fiona Ulph and Yalda Jamshidi",

note = "Funding Information: IP has received funding from the World Cancer Research Fund (WCRF UK) and World Cancer Research Fund International (2017/1641), the European Union{\textquoteright}s Horizon 2020 research and innovation programme (LONGITOOLS, H2020-SC1-2019-874739), the Ministry of Science and Higher Education of Russian Federation (075-15-2021-595), Agence Nationale de la Recherche (PreciDIAB, ANR-18-IBHU-0001), the European Union through the “Fonds europ{\'e}en de d{\'e}veloppement regional” (FEDER), the “Conseil R{\'e}gional des Hauts-de-France” (Hauts-de-France Regional Council), and the “M{\'e}tropole Europ{\'e}enne de Lille” (MEL, European Metropolis of Lille).",

year = "2021",

doi = "https://doi.org/10.1038/s41431-021-01000-x",

language = "English",

journal = "European journal of human genetics",

issn = "1018-4813",

publisher = "Nature Publishing Group",

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The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice. / on behalf of the Executive Committee of the European Society of Human Genetics; the Public and Professional Policy Committee of the European Society of Human Genetics.
In: European journal of human genetics, 2021.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - The use of polygenic risk scores in pre-implantation genetic testing

T2 - an unproven, unethical practice

AU - Forzano, Francesca

AU - Antonova, Olga

AU - Clarke, Angus

AU - de Wert, Guido

AU - Hentze, Sabine

AU - Jamshidi, Yalda

AU - Moreau, Yves

AU - Perola, Markus

AU - Prokopenko, Inga

AU - Read, Andrew

AU - Reymond, Alexandre

AU - Stefansdottir, Vigdis

AU - van el, Carla

AU - Genuardi, Maurizio

AU - Peterlin, Borut

AU - Oliveira, Carla

AU - Writzl, Karin

AU - Houge, Gunnar Douzgos

AU - Cordier, Christophe

AU - Howard, Heidi

AU - Macek, Milan

AU - Melegh, B. la

AU - Mendes, Alvaro

AU - Radojkovic, Dragica

AU - on behalf of the Executive Committee of the European Society of Human Genetics

AU - Rial-Sebbag, Emmanuelle

AU - the Public and Professional Policy Committee of the European Society of Human Genetics

AU - Ulph, Fiona

AU - Jamshidi, Yalda

N1 - Funding Information: IP has received funding from the World Cancer Research Fund (WCRF UK) and World Cancer Research Fund International (2017/1641), the European Union’s Horizon 2020 research and innovation programme (LONGITOOLS, H2020-SC1-2019-874739), the Ministry of Science and Higher Education of Russian Federation (075-15-2021-595), Agence Nationale de la Recherche (PreciDIAB, ANR-18-IBHU-0001), the European Union through the “Fonds européen de développement regional” (FEDER), the “Conseil Régional des Hauts-de-France” (Hauts-de-France Regional Council), and the “Métropole Européenne de Lille” (MEL, European Metropolis of Lille).

PY - 2021

Y1 - 2021

UR - http://www.scopus.com/inward/record.url?scp=85121535929&partnerID=8YFLogxK

U2 - https://doi.org/10.1038/s41431-021-01000-x

DO - https://doi.org/10.1038/s41431-021-01000-x

M3 - Article

C2 - 34916614

SN - 1018-4813

JO - European journal of human genetics

JF - European journal of human genetics

ER -

on behalf of the Executive Committee of the European Society of Human Genetics, the Public and Professional Policy Committee of the European Society of Human Genetics. The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice. European journal of human genetics. 2021. Epub 2021. doi: https://doi.org/10.1038/s41431-021-01000-x

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

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