Tissue engineering in burn scar reconstruction

P. P.M. Van Zuijlen, K. L.M. Gardien, M. E.H. Jaspers, E. J. Bos, D. C. Baas, A. J.M. Van Trier, E. Middelkoop

Research output: Contribution to journalReview articleAcademicpeer-review

31 Citations (Scopus)


Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

Original languageEnglish
Article number18
JournalBurns & trauma
Issue number1
Publication statusPublished - 2015


  • Burns
  • Cartilage
  • Contracture
  • Reconstruction
  • Scar
  • Subcutaneous fat tissue
  • Substitute
  • Tissue engineering

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