Toepassing van probiotische lactobacillen bij kinderen met gastro-intestinale klachten: Nog weinig evidence

M. M. Tabbers, M. A. Benninga

Research output: Contribution to journalReview articleProfessional

6 Citations (Scopus)


- Probiotics are defined as 'live micro-organisms that confer a health benefit on the host if administered in adequate amounts'. - There are only limited data in the literature regarding the efficacy and safety of lactobacilli for various gastrointestinal indications in children. - Lactobacillus rhamnosus GG (LGG) has no added value in the treatment of children with functional constipation. - Lactobacilli do seem to be effective in rotavirus diarrhoea. They seem safe and shorten the duration of the diarrhoea by about 1 day. - For the prevention of infectious diarrhoea, lactobacilli are only moderately effective and the clinical relevance is unclear. - There is 1 controlled study in which LGG had a preventive effect on the development of atopic eczema (but not of allergy to cow's milk) in newborn infants.
Original languageDutch
Pages (from-to)2198-2202
JournalNederlands Tijdschrift voor Geneeskunde
Issue number40
Publication statusPublished - 2007

Cite this