Transmission dynamics and control of severe acute respiratory syndrome

Marc Lipsitch; Ted Cohen; Ben Cooper; James M. Robins; Stefan Ma; Lyn James; Gowri Gopalakrishna; Suok Kai Chew; Chorh Chuan Tan; Matthew H. Samore; David Fisman; Megan Murray

doi:https://doi.org/10.1126/science.1086616

Transmission dynamics and control of severe acute respiratory syndrome

Marc Lipsitch, Ted Cohen, Ben Cooper, James M. Robins, Stefan Ma, Lyn James, Gowri Gopalakrishna, Suok Kai Chew, Chorh Chuan Tan, Matthew H. Samore, David Fisman, Megan Murray

Research output: Contribution to journal › Article › Academic › peer-review

1110 Citations (Scopus)

Abstract

Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemloiogic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Pubiic-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

Original language	English
Pages (from-to)	1966-1970
Number of pages	5
Journal	Science
Volume	300
Issue number	5627
DOIs	https://doi.org/10.1126/science.1086616
Publication status	Published - 20 Jun 2003

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title = "Transmission dynamics and control of severe acute respiratory syndrome",

abstract = "Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemloiogic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Pubiic-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.",

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AU - Lipsitch, Marc

AU - Cohen, Ted

AU - Cooper, Ben

AU - Robins, James M.

AU - Ma, Stefan

AU - James, Lyn

AU - Gopalakrishna, Gowri

AU - Chew, Suok Kai

AU - Tan, Chorh Chuan

AU - Samore, Matthew H.

AU - Fisman, David

AU - Murray, Megan

PY - 2003/6/20

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N2 - Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemloiogic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Pubiic-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

AB - Severe acute respiratory syndrome (SARS) is a recently described illness of humans that has spread widely over the past 6 months. With the use of detailed epidemloiogic data from Singapore and epidemic curves from other settings, we estimated the reproductive number for SARS in the absence of interventions and in the presence of control efforts. We estimate that a single infectious case of SARS will infect about three secondary cases in a population that has not yet instituted control measures. Pubiic-health efforts to reduce transmission are expected to have a substantial impact on reducing the size of the epidemic.

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SN - 0036-8075

VL - 300

SP - 1966

EP - 1970

JO - Science

JF - Science

IS - 5627

ER -

Transmission dynamics and control of severe acute respiratory syndrome

Abstract

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