TY - JOUR
T1 - Two-year efficacy and safety of Simvastatin 80 mg in familial hypercholesterolemia (The examination of probands and relatives in statin studies with familial hypercholesterolemia [ExPRESS FH])
AU - de Sauvage Nolting, Pernette R. W.
AU - Buirma, Rudolf J. A.
AU - Hutten, Barbara A.
AU - Kastelein, John J. P.
PY - 2002
Y1 - 2002
N2 - High-dose (80 mg) simvastatin is efficacious in both reducing low-density lipoprotein cholesterol (-48%) and triglyceride (-26%) levels and in elevating high-density lipoprotein cholesterol (+ 13%) levels in a large cohort of patients with familial hypercholesterolemia. No tachyphylaxis was seen during a 2-year treatment period, and therapy with simvastatin 80 mg was well tolerated
AB - High-dose (80 mg) simvastatin is efficacious in both reducing low-density lipoprotein cholesterol (-48%) and triglyceride (-26%) levels and in elevating high-density lipoprotein cholesterol (+ 13%) levels in a large cohort of patients with familial hypercholesterolemia. No tachyphylaxis was seen during a 2-year treatment period, and therapy with simvastatin 80 mg was well tolerated
M3 - Article
C2 - 12106856
SN - 0002-9149
VL - 90
SP - 181-+
JO - American Journal of Cardiology
JF - American Journal of Cardiology
IS - 2
ER -