Urine analysis by laser Raman spectroscopy

P. W A Willems; W. Peter Vandertop; Rudolf M. Verdaasdonk; C. F P Van Swol; Gerard H. Jansen

doi:https://doi.org/10.1002/lsm.1058

Urine analysis by laser Raman spectroscopy

P. W A Willems, W. Peter Vandertop, Rudolf M. Verdaasdonk, C. F P Van Swol, Gerard H. Jansen

Research output: Contribution to journal › Article › Academic › peer-review

109 Citations (Scopus)

Abstract

Background and Objective: We examine the use of Raman spectroscopy to analyze components in human urine. Study Design/Methods and Meterials: Targeted urine components include urea, uric acid, and creatinine. Results: Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface-enhanced Raman spectroscopic methods (SERS). Conclusion: Both normal Raman and SERS approaches have been investigated for total urine-nitrogen determination, urine urea-nitrogen determination, and for the urea/ creatinine excretion ratio.

Original language	English
Pages (from-to)	330-334
Number of pages	5
Journal	Lasers in surgery and medicine
Volume	28
Issue number	4
DOIs	https://doi.org/10.1002/lsm.1058
Publication status	Published - 17 May 2001

Keywords

Creatinine
Gold colloid
Portable spectrometer
Surface-enhanced Raman spectroscopy
Uric acid

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title = "Urine analysis by laser Raman spectroscopy",

abstract = "Background and Objective: We examine the use of Raman spectroscopy to analyze components in human urine. Study Design/Methods and Meterials: Targeted urine components include urea, uric acid, and creatinine. Results: Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface-enhanced Raman spectroscopic methods (SERS). Conclusion: Both normal Raman and SERS approaches have been investigated for total urine-nitrogen determination, urine urea-nitrogen determination, and for the urea/ creatinine excretion ratio.",

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T1 - Urine analysis by laser Raman spectroscopy

AU - Willems, P. W A

AU - Peter Vandertop, W.

AU - Verdaasdonk, Rudolf M.

AU - Van Swol, C. F P

AU - Jansen, Gerard H.

PY - 2001/5/17

Y1 - 2001/5/17

N2 - Background and Objective: We examine the use of Raman spectroscopy to analyze components in human urine. Study Design/Methods and Meterials: Targeted urine components include urea, uric acid, and creatinine. Results: Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface-enhanced Raman spectroscopic methods (SERS). Conclusion: Both normal Raman and SERS approaches have been investigated for total urine-nitrogen determination, urine urea-nitrogen determination, and for the urea/ creatinine excretion ratio.

AB - Background and Objective: We examine the use of Raman spectroscopy to analyze components in human urine. Study Design/Methods and Meterials: Targeted urine components include urea, uric acid, and creatinine. Results: Urea concentration in urine is sufficiently high that normal Raman spectroscopy may be used for its analysis. All other components are in low concentrations requiring the use of surface-enhanced Raman spectroscopic methods (SERS). Conclusion: Both normal Raman and SERS approaches have been investigated for total urine-nitrogen determination, urine urea-nitrogen determination, and for the urea/ creatinine excretion ratio.

KW - Creatinine

KW - Gold colloid

KW - Portable spectrometer

KW - Surface-enhanced Raman spectroscopy

KW - Uric acid

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VL - 28

SP - 330

EP - 334

JO - Lasers in surgery and medicine

JF - Lasers in surgery and medicine

IS - 4

ER -

Urine analysis by laser Raman spectroscopy

Abstract

Keywords

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