TY - JOUR
T1 - Use of Buprenorphine in Children With Chronic Pseudoobstruction Syndrome Case Series and Review of Literature
AU - Prapaitrakool, Sunisa
AU - Hollmann, Markus W.
AU - Wartenberg, Hans Christian
AU - Preckel, Benedikt
AU - Brugger, Stefan
PY - 2012
Y1 - 2012
N2 - Objectives: Abdominal pain is the most challenging symptom in chronic intestinal pseudoobstruction (CIPO) syndrome, because of its severity and the limited availability of suitable opioid formulations, especially in pediatric patients with digestive problems. Most of the children with CIPO cannot tolerate oral formulations. Case Reports: We present 4 cases of children with CIPO and severe intractable abdominal pain, and report on the use of a recently available form of opioid, transdermal buprenorphine in a dosage of 5 mcg/h. Discussion: CIPO and the unique pharmacological profile of buprenorphine are reviewed briefly
AB - Objectives: Abdominal pain is the most challenging symptom in chronic intestinal pseudoobstruction (CIPO) syndrome, because of its severity and the limited availability of suitable opioid formulations, especially in pediatric patients with digestive problems. Most of the children with CIPO cannot tolerate oral formulations. Case Reports: We present 4 cases of children with CIPO and severe intractable abdominal pain, and report on the use of a recently available form of opioid, transdermal buprenorphine in a dosage of 5 mcg/h. Discussion: CIPO and the unique pharmacological profile of buprenorphine are reviewed briefly
U2 - https://doi.org/10.1097/AJP.0b013e318243f609
DO - https://doi.org/10.1097/AJP.0b013e318243f609
M3 - Review article
C2 - 22688601
SN - 0749-8047
VL - 28
SP - 722
EP - 725
JO - Clinical journal of pain
JF - Clinical journal of pain
IS - 8
ER -