Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall

Freek J. Van der Meer; Dirk J. Faber; Maurice C. Aalders; Ton G. Van Leeuwen

doi:https://doi.org/10.1117/12.477883

Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall

Freek J. Van der Meer, Dirk J. Faber, Maurice C. Aalders, Ton G. Van Leeuwen

Research output: Contribution to conference › Abstract › Academic

Abstract

The feasibility to detect and characterize vulnerable plaques by Optical Coherence Tomography (OCT) is currently under investigation. It has been shown that in some cases, by using qualitative criteria, the OCT images can be used to differentiate between different types of plaque. However, the quality of the image and the experience of the observer greatly influences the interpretation of the images, which indicates the necessity of a quantitative analysis of the OCT data. As OCT measures the depth resolved backscattering it is possible to calculate the light attenuation coefficient (μ_t) in the different areas in the image and use that to identify the different plaque constituents in the target tissue. In this study, we present in vitro data on μ _t, measured in atherosclerotic lesions.

Original language	English
Pages	495-499
Number of pages	5
DOIs	https://doi.org/10.1117/12.477883
Publication status	Published - 2003
Event	Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII - San Jose,CA, United States Duration: 25 Jan 2003 → 26 Jan 2003

Conference

Conference	Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII
Country/Territory	United States
City	San Jose,CA
Period	25/01/2003 → 26/01/2003

Keywords

Backscattering
OCT
Optical coherence tomography
Optical properties

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https://doi.org/10.1117/12.477883

Cite this

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title = "Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall",

abstract = "The feasibility to detect and characterize vulnerable plaques by Optical Coherence Tomography (OCT) is currently under investigation. It has been shown that in some cases, by using qualitative criteria, the OCT images can be used to differentiate between different types of plaque. However, the quality of the image and the experience of the observer greatly influences the interpretation of the images, which indicates the necessity of a quantitative analysis of the OCT data. As OCT measures the depth resolved backscattering it is possible to calculate the light attenuation coefficient (μt) in the different areas in the image and use that to identify the different plaque constituents in the target tissue. In this study, we present in vitro data on μ t, measured in atherosclerotic lesions.",

keywords = "Backscattering, OCT, Optical coherence tomography, Optical properties",

author = "{Van der Meer}, {Freek J.} and Faber, {Dirk J.} and Aalders, {Maurice C.} and {Van Leeuwen}, {Ton G.}",

year = "2003",

doi = "https://doi.org/10.1117/12.477883",

language = "English",

pages = "495--499",

note = "Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII ; Conference date: 25-01-2003 Through 26-01-2003",

}

Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall. / Van der Meer, Freek J.; Faber, Dirk J.; Aalders, Maurice C. et al.
2003. 495-499 Abstract from Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII, San Jose,CA, United States.

Research output: Contribution to conference › Abstract › Academic

TY - CONF

T1 - Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall

AU - Van der Meer, Freek J.

AU - Faber, Dirk J.

AU - Aalders, Maurice C.

AU - Van Leeuwen, Ton G.

PY - 2003

Y1 - 2003

N2 - The feasibility to detect and characterize vulnerable plaques by Optical Coherence Tomography (OCT) is currently under investigation. It has been shown that in some cases, by using qualitative criteria, the OCT images can be used to differentiate between different types of plaque. However, the quality of the image and the experience of the observer greatly influences the interpretation of the images, which indicates the necessity of a quantitative analysis of the OCT data. As OCT measures the depth resolved backscattering it is possible to calculate the light attenuation coefficient (μt) in the different areas in the image and use that to identify the different plaque constituents in the target tissue. In this study, we present in vitro data on μ t, measured in atherosclerotic lesions.

AB - The feasibility to detect and characterize vulnerable plaques by Optical Coherence Tomography (OCT) is currently under investigation. It has been shown that in some cases, by using qualitative criteria, the OCT images can be used to differentiate between different types of plaque. However, the quality of the image and the experience of the observer greatly influences the interpretation of the images, which indicates the necessity of a quantitative analysis of the OCT data. As OCT measures the depth resolved backscattering it is possible to calculate the light attenuation coefficient (μt) in the different areas in the image and use that to identify the different plaque constituents in the target tissue. In this study, we present in vitro data on μ t, measured in atherosclerotic lesions.

KW - Backscattering

KW - OCT

KW - Optical coherence tomography

KW - Optical properties

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U2 - https://doi.org/10.1117/12.477883

DO - https://doi.org/10.1117/12.477883

M3 - Abstract

SP - 495

EP - 499

T2 - Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII

Y2 - 25 January 2003 through 26 January 2003

ER -

Using Optical Coherence Tomography (OCT) for Quantitative Measurement of Attenuation Coefficients of the Arterial Wall

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Conference

Keywords

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