Uterine Artery Embolization for the Treatment of Adenomyosis: A Systematic Review and Meta-Analysis

Annefleur M. de Bruijn, Marieke Smink, Paul N.M. Lohle, Judith A.F. Huirne, Jos W.R. Twisk, Caroline Wong, Linda Schoonmade, Wouter J.K. Hehenkamp

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65 Citations (Scopus)


The effect of uterine artery embolization (UAE) on symptomatic adenomyosis was evaluated in a systematic review and meta-analysis. Four groups were evaluated: short-term (< 12 months) pure adenomyosis, short-term adenomyosis with fibroids (combined adenomyosis), long-term (> 12 months) pure adenomyosis, and long-term combined adenomyosis. Improvement of symptoms occurred in 83.1% (872/1,049) of patients. Reported symptom reduction was 4.8% greater in the short-term combined group (P = .169) and 11.4% greater in the long-term combined group (P = .003). Uterine volume was reduced in all patients at 3 months. The effects of UAE on symptom improvement and uterine volume reduction in patients with adenomyosis are encouraging.

Original languageEnglish
JournalJournal of vascular and interventional radiology
Issue number12
Publication statusPublished - Dec 2017

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