TY - JOUR
T1 - Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting
AU - van Geel, Nanja
AU - Wolkerstorfer, Albert
AU - Ezzedine, Khaled
AU - Pandya, Amit G.
AU - Bekkenk, Marcel
AU - Grine, Lynda
AU - van Belle, Sarah
AU - Lommerts, Janny E.
AU - Hamzavi, Iltefat
AU - Harris, John E.
AU - Eleftheriadou, Viktoria
AU - Esmat, Samia
AU - Kang, Hee Young
AU - Kumarasinghe, Prasad
AU - Lan, Cheng-Che E.
AU - Parsad, Davinder
AU - Raboobee, Noufal
AU - Flora Xiang, Leihong
AU - Suzuki, Tamio
AU - Prinsen, Cecilia A.
AU - Taieb, Alain
AU - Picardo, Mauro
AU - Speeckaert, Reinhart
AU - the participants of the Rome International VGICC /VIS Workshop
AU - Anbar, Tag
AU - Anbar, Mohamed
AU - Benzekri, Laïla
AU - Böhm, Markus
AU - Castro, Caïo
AU - Cestari, Tania
AU - Gauthier, Yvon
AU - Gnarra, Maria
AU - Hinojosa, Jorge
AU - Jung, Min Bae
AU - Katayama, Ichiro
AU - Kim, Ki-Ho
AU - Eric Lan, Cheng-Che
AU - Lee, Seung-Chung
AU - le Poole, Caroline
AU - Lim, Henry
AU - Moretti, Silvia
AU - Seneschal, Julien
AU - Spritz, Richard
AU - van Geel, Nanja
AU - Xiang, Flora
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.
AB - Currently, vitiligo lacks a validated Physician Global Assessment (PGA) for disease extent. This PGA can be used to stratify and interpret the numeric scores obtained by the Vitiligo Extent Score (VES). We investigated the interrater reliability of a 5-point PGA scale during an international vitiligo workshop. Vitiligo experts from five different continents rated photographs of non-segmental vitiligo patients with varying degrees of extent with the PGA score. Good interrater agreements (intraclass correlation coefficient >0.6) were observed between the raters overall and within each continent. All hypotheses to evaluate construct validity were confirmed. Median VES values per category were for limited 1.10 [IQR: 0.21–1.67], moderate 3.17 [IQR: 1.75–6.21], extensive 9.58 [IQR: 6.21–13.03] and very extensive 42.67 [IQR: 21.20–42.67]. Defined categories for vitiligo extent can be valuable for inclusion criteria and may impact future reimbursement criteria.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85065641370&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/30945409
U2 - https://doi.org/10.1111/pcmr.12784
DO - https://doi.org/10.1111/pcmr.12784
M3 - Article
C2 - 30945409
SN - 1755-1471
VL - 32
SP - 728
EP - 733
JO - Pigment Cell and Melanoma Research
JF - Pigment Cell and Melanoma Research
IS - 5
ER -