Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease

M. C. van Aalderen; K. Brinkman; G. E. L. van den Berk; W. E. Terpstra

Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease

M. C. van Aalderen, K. Brinkman, G. E. L. van den Berk, W. E. Terpstra

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Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Abstract

An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly. An FDG-PET-scan-guided lymph node biopsy revealed the characteristic histological features of the plasma cell variant of Castleman's disease. A high HHV-8 viral load was detected in the serum (7980 copies/ml). Treatment with HAART, rituximab and vinblastine resulted in a full and rapid recovery and lowered HHV-8 viral load to undetectable levels

Original language	English
Pages (from-to)	87-90
Journal	Netherlands journal of medicine
Volume	68
Issue number	2
Publication status	Published - 2010

Cite this

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title = "Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease",

abstract = "An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly. An FDG-PET-scan-guided lymph node biopsy revealed the characteristic histological features of the plasma cell variant of Castleman's disease. A high HHV-8 viral load was detected in the serum (7980 copies/ml). Treatment with HAART, rituximab and vinblastine resulted in a full and rapid recovery and lowered HHV-8 viral load to undetectable levels",

author = "{van Aalderen}, {M. C.} and K. Brinkman and {van den Berk}, {G. E. L.} and Terpstra, {W. E.}",

year = "2010",

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volume = "68",

pages = "87--90",

journal = "Netherlands journal of medicine",

issn = "0300-2977",

publisher = "Van Zuiden Communications BV",

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TY - JOUR

T1 - Vinblastine, rituximab and HAART, treatment of an HIV -positive patient with multicentric Castleman's disease

AU - van Aalderen, M. C.

AU - Brinkman, K.

AU - van den Berk, G. E. L.

AU - Terpstra, W. E.

PY - 2010

Y1 - 2010

N2 - An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly. An FDG-PET-scan-guided lymph node biopsy revealed the characteristic histological features of the plasma cell variant of Castleman's disease. A high HHV-8 viral load was detected in the serum (7980 copies/ml). Treatment with HAART, rituximab and vinblastine resulted in a full and rapid recovery and lowered HHV-8 viral load to undetectable levels

AB - An HIV-positive man from Somalia presented with severe malaise, weight loss, relapsing fever, lymphadenopathy and splenomegaly. An FDG-PET-scan-guided lymph node biopsy revealed the characteristic histological features of the plasma cell variant of Castleman's disease. A high HHV-8 viral load was detected in the serum (7980 copies/ml). Treatment with HAART, rituximab and vinblastine resulted in a full and rapid recovery and lowered HHV-8 viral load to undetectable levels

M3 - Article

C2 - 20167961

SN - 0300-2977

VL - 68

SP - 87

EP - 90

JO - Netherlands journal of medicine

JF - Netherlands journal of medicine

IS - 2

ER -