Web-based intervention for depressive symptoms in adults with types 1 and 2 diabetes mellitus: A health economic evaluation

Stephanie Nobis, David Daniel Ebert, Dirk Lehr, Filip Smit, Claudia Buntrock, Matthias Berking, Harald Baumeister, Frank Snoek, Burkhardt Funk, Heleen Riper

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)


Background: Web-based interventions are effective in reducing depression. However, the evidence for the cost-effectiveness of these interventions is scarce. Aims: The aim is to assess the cost-effectiveness of a web-based intervention (GET.ON M.E.D.) for individuals with diabetes and comorbid depression compared with an active control group receiving web-based psychoeducation. Method: We conducted a cost-effectiveness analysis with treatment response as the outcome and a cost-utility analysis with qualityadjusted life-years (QALYs) alongside a randomised controlled trial with 260 participants. Results: At a willingness-to-pay ceiling of €5000 for a treatment response, the intervention has a 97% probability of being regarded as costeffective compared with the active control group. If society is willing to pay €14 000 for an additional QALY, the intervention has a 51% probability of being cost-effective. Conclusions: This web-based intervention for individuals with diabetes and comorbid depression demonstrated a high probability of being cost-effective compared with an active control group.

Original languageEnglish
Pages (from-to)199-206
Number of pages8
JournalBritish journal of psychiatry
Issue number4
Early online date4 Mar 2018
Publication statusPublished - 1 Apr 2018

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