What do we measure when we measure cell-associated HIV RNA

Alexander O. Pasternak; Ben Berkhout

doi:https://doi.org/10.1186/s12977-018-0397-2

What do we measure when we measure cell-associated HIV RNA

Alexander O. Pasternak, Ben Berkhout

Research output: Contribution to journal › Review article › Academic › peer-review

63 Citations (Scopus)

Abstract

Cell-associated (CA) HIV RNA has received much attention in recent years as a surrogate measure of the efficiency of HIV latency reversion and because it may provide an estimate of the viral reservoir size. This review provides an update on some recent insights in the biology and clinical utility of this biomarker. We discuss a number of important considerations to be taken into account when interpreting CA HIV RNA measurements, as well as different methods to measure this biomarker

Original language	English
Pages (from-to)	13
Journal	Retrovirology
Volume	15
Issue number	1
DOIs	https://doi.org/10.1186/s12977-018-0397-2
Publication status	Published - 2018

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https://doi.org/10.1186/s12977-018-0397-2

Cite this

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AB - Cell-associated (CA) HIV RNA has received much attention in recent years as a surrogate measure of the efficiency of HIV latency reversion and because it may provide an estimate of the viral reservoir size. This review provides an update on some recent insights in the biology and clinical utility of this biomarker. We discuss a number of important considerations to be taken into account when interpreting CA HIV RNA measurements, as well as different methods to measure this biomarker

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DO - https://doi.org/10.1186/s12977-018-0397-2

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