What next for preimplantation genetic screening? More randomized controlled trials needed?

S. Mastenbroek, P. Scriven, M. Twisk, S. Viville, F. van der Veen, S. Repping

Research output: Contribution to journalArticleAcademicpeer-review

49 Citations (Scopus)

Abstract

The recent debate on preimplantation genetic screening (PGS) has raised questions about its routine use in clinical practice. It has been suggested that the most effective way to resolve the debate about the usefulness of PGS is to perform more well-designed and well-executed randomized controlled trials (RCTs). However, in view of the lack of evidence for the effectiveness of PGS and the accumulating evidence for its harmfulness, it is our opinion that it is unethical to perform additional RCTs for the indication advanced maternal age using cleavage stage biopsy
Original languageEnglish
Pages (from-to)2626-2628
JournalHuman reproduction (Oxford, England)
Volume23
Issue number12
DOIs
Publication statusPublished - 2008

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