TY - CHAP
T1 - Why, when and how to assess ischemia and viability in patients with chronic total occlusions
AU - van Veelen, Anna
AU - Schumacher, Stefan P.
AU - Stuijfzand, Wynand J.
AU - Henriques, José P S
AU - Knaapen, Paul
AU - Stuijfzand, Wijnand J. A.
PY - 2022/11/23
Y1 - 2022/11/23
N2 - Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.
AB - Currently, international guidelines recommend the evaluation of ischemic symptoms, as well as the extent of ischemia and the presence of viability, prior to referring patients with stable coronary artery disease, including chronic total occlusion (CTO), for revascularization. A few randomized trials and numerous observational studies have tried to determine the value of ischemia-driven and viability-driven revascularization, but demonstrated contradicting findings. The present review will focus on the current knowledge regarding ischemia and viability testing in patients with a CTO. The evidence and rationale to assess ischemia and viability, next to the clinical workup for CTO revascularization in clinical practice, will be discussed. In addition, an overview of available noninvasive imaging modalities to assess the presence and extent of ischemia and viability will be provided.
UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85153996191&origin=inward
UR - https://www.ncbi.nlm.nih.gov/pubmed/36532703
U2 - https://doi.org/10.1007/978-3-031-05437-2_4
DO - https://doi.org/10.1007/978-3-031-05437-2_4
M3 - Chapter
C2 - 36532703
SN - 9783031054365
T3 - Percutaneous Coronary Intervention for Chronic Total Occlusion: The Hybrid Approach
SP - 27
EP - 42
BT - Percutaneous Coronary Intervention for Chronic Total Occlusion
A2 - Rinfret, Stéphane
PB - Springer International Publishing
CY - Cham
ER -