Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment

Behnood Bikdeli; Candrika D. Khairani; Briana M. Barns; Rachel P. Rosovsky; David Jimenez; Manuel Monreal; Katelyn W. Sylvester; Saskia Middeldorp; Shannon M. Bates; Harlan M. Krumholz; Samuel Z. Goldhaber; Beverley J. Hunt; Gregory Piazza

doi:https://doi.org/10.1016/j.cct.2022.106714

Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment

Behnood Bikdeli, Candrika D. Khairani, Briana M. Barns, Rachel P. Rosovsky, David Jimenez, Manuel Monreal, Katelyn W. Sylvester, Saskia Middeldorp, Shannon M. Bates, Harlan M. Krumholz, Samuel Z. Goldhaber, Beverley J. Hunt, Gregory Piazza

Research output: Contribution to journal › Article › Academic › peer-review

3 Citations (Scopus)

Original language	English
Article number	106714
Journal	Contemporary clinical trials
Volume	115
DOIs	https://doi.org/10.1016/j.cct.2022.106714
Publication status	Published - 1 Apr 2022

Keywords

Anticoagulation
Direct
Randomized controlled trial
Women

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https://doi.org/10.1016/j.cct.2022.106714

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Bikdeli, B., Khairani, C. D., Barns, B. M., Rosovsky, R. P., Jimenez, D., Monreal, M., Sylvester, K. W., Middeldorp, S., Bates, S. M., Krumholz, H. M., Goldhaber, S. Z., Hunt, B. J., & Piazza, G. (2022). Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment. Contemporary clinical trials, 115, Article 106714. https://doi.org/10.1016/j.cct.2022.106714

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title = "Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment",

keywords = "Anticoagulation, Direct, Randomized controlled trial, Women",

author = "Behnood Bikdeli and Khairani, {Candrika D.} and Barns, {Briana M.} and Rosovsky, {Rachel P.} and David Jimenez and Manuel Monreal and Sylvester, {Katelyn W.} and Saskia Middeldorp and Bates, {Shannon M.} and Krumholz, {Harlan M.} and Goldhaber, {Samuel Z.} and Hunt, {Beverley J.} and Gregory Piazza",

note = "Funding Information: Dr. Bikdeli is a recipient of the IGNITE Award from the Mary Horrigan Connors Center for Women's Health and Gender Biology at Brigham and Women's Hospital. Funding Information: Dr. Bikdeli reports that he is a consulting expert, on behalf of the plaintiff, for litigation related to two specific brand models of IVC filters. Dr. Rosovsky reports research grant support to her institution from Janssen and Bristol Myers Squibb and consultant/advisory fees from Janssen, Bristol Myers Squibb, Dova and Inari, all outside the scope of this work. Dr. Bates receives unencumbered salary support from the Eli Lilly Canada/May Cohen Chair in Women's Health. Dr. Krumholz reported receiving personal fees from UnitedHealth, IBM Watson Health, Element Science, Aetna, Facebook, Siegfried & Jensen Law Firm, Arnold & Porter Law Firm, Martin/Baughman Law Firm, F-Prime, and the National Center for Cardiovascular Diseases, Beijing; being the cofounder of HugoHealth, a personal health information platform, and Refactor Health, an enterprise health care artificial intelligence–augmented data management company; receiving contracts from the Centers for Medicare & Medicaid Services, through Yale New Haven Hospital, to develop and maintain measures of hospital performance; and receiving grants from Medtronic, the US Food and Drug Administration, Johnson & Johnson, and the Shenzhen Center for Health Information outside the submitted work. Dr. Goldhaber has received research support from Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Boston Scientific, Daiichi-Sankyo, Janssen, the National Heart, Lung, and Blood Institute, and the Thrombosis Research Institute; and has received consulting fees from Bayer, Agile, Boston Scientific, and Boehringer Ingelheim. Dr. Piazza has received research grant support from Boston Scientific Corporation, Bayer, Bristol Myers Squibb/Pfizer, Portola/Alexion Pharmaceuticals, and Janssen Pharmaceuticals; and has received consulting fees from Amgen, Pfizer, Agile, and Prairie Education and Research Cooperative.",

year = "2022",

month = apr,

day = "1",

doi = "https://doi.org/10.1016/j.cct.2022.106714",

language = "English",

volume = "115",

journal = "Contemporary clinical trials",

issn = "1551-7144",

publisher = "Elsevier Inc.",

}

Bikdeli, B, Khairani, CD, Barns, BM, Rosovsky, RP, Jimenez, D, Monreal, M, Sylvester, KW, Middeldorp, S, Bates, SM, Krumholz, HM, Goldhaber, SZ, Hunt, BJ & Piazza, G 2022, 'Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment', Contemporary clinical trials, vol. 115, 106714. https://doi.org/10.1016/j.cct.2022.106714

Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment. / Bikdeli, Behnood; Khairani, Candrika D.; Barns, Briana M. et al.
In: Contemporary clinical trials, Vol. 115, 106714, 01.04.2022.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Women's representation in venous thromboembolism randomized trials and registries

T2 - The illustrative example of direct oral anticoagulants for acute treatment

AU - Bikdeli, Behnood

AU - Khairani, Candrika D.

AU - Barns, Briana M.

AU - Rosovsky, Rachel P.

AU - Jimenez, David

AU - Monreal, Manuel

AU - Sylvester, Katelyn W.

AU - Middeldorp, Saskia

AU - Bates, Shannon M.

AU - Krumholz, Harlan M.

AU - Goldhaber, Samuel Z.

AU - Hunt, Beverley J.

AU - Piazza, Gregory

N1 - Funding Information: Dr. Bikdeli is a recipient of the IGNITE Award from the Mary Horrigan Connors Center for Women's Health and Gender Biology at Brigham and Women's Hospital. Funding Information: Dr. Bikdeli reports that he is a consulting expert, on behalf of the plaintiff, for litigation related to two specific brand models of IVC filters. Dr. Rosovsky reports research grant support to her institution from Janssen and Bristol Myers Squibb and consultant/advisory fees from Janssen, Bristol Myers Squibb, Dova and Inari, all outside the scope of this work. Dr. Bates receives unencumbered salary support from the Eli Lilly Canada/May Cohen Chair in Women's Health. Dr. Krumholz reported receiving personal fees from UnitedHealth, IBM Watson Health, Element Science, Aetna, Facebook, Siegfried & Jensen Law Firm, Arnold & Porter Law Firm, Martin/Baughman Law Firm, F-Prime, and the National Center for Cardiovascular Diseases, Beijing; being the cofounder of HugoHealth, a personal health information platform, and Refactor Health, an enterprise health care artificial intelligence–augmented data management company; receiving contracts from the Centers for Medicare & Medicaid Services, through Yale New Haven Hospital, to develop and maintain measures of hospital performance; and receiving grants from Medtronic, the US Food and Drug Administration, Johnson & Johnson, and the Shenzhen Center for Health Information outside the submitted work. Dr. Goldhaber has received research support from Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Boston Scientific, Daiichi-Sankyo, Janssen, the National Heart, Lung, and Blood Institute, and the Thrombosis Research Institute; and has received consulting fees from Bayer, Agile, Boston Scientific, and Boehringer Ingelheim. Dr. Piazza has received research grant support from Boston Scientific Corporation, Bayer, Bristol Myers Squibb/Pfizer, Portola/Alexion Pharmaceuticals, and Janssen Pharmaceuticals; and has received consulting fees from Amgen, Pfizer, Agile, and Prairie Education and Research Cooperative.

PY - 2022/4/1

Y1 - 2022/4/1

KW - Anticoagulation

KW - Direct

KW - Randomized controlled trial

KW - Women

UR - http://www.scopus.com/inward/record.url?scp=85125172335&partnerID=8YFLogxK

U2 - https://doi.org/10.1016/j.cct.2022.106714

DO - https://doi.org/10.1016/j.cct.2022.106714

M3 - Article

C2 - 35202841

SN - 1551-7144

VL - 115

JO - Contemporary clinical trials

JF - Contemporary clinical trials

M1 - 106714

ER -

Women's representation in venous thromboembolism randomized trials and registries: The illustrative example of direct oral anticoagulants for acute treatment

Keywords

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