Yttrium radiosynoviorthesis in the treatment of knee arthritis in rheumatoid arthritis: A systematic review

L. L.J. Heuft-Dorenbosch, H. C.W. De Vet, S. Van der Linden

Research output: Contribution to journalReview articleAcademicpeer-review

77 Citations (Scopus)


Objective - To consider the question: How strong is the evidence in favour of yttrium synovectomy in chronic knee arthritis in patients with rheumatoid arthritis in comparison with placebo and intra-articular steroid treatment? Methods - A systematic review of the literature was performed using Medline and the Embase database. Results - Initially, seven papers were identified, but only two met the inclusion criteria. Neither study showed evidence in favour of yttrium synovectomy. Conclusion - From the point of view of evidence based medicine it should be seriously questioned whether yttrium synovectomy deserves a place in clinical practice.

Original languageEnglish
Pages (from-to)583-586
Number of pages4
JournalAnnals of the rheumatic diseases
Issue number8
Publication statusPublished - 23 Aug 2000

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