Folkert Asselbergs

2018

Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation

Thorolfsdottir, RB., Sveinbjornsson, G., Sulem, P., Nielsen, JB., Jonsson, S., Halldorsson, GH., Melsted, P., Ivarsdottir, EV., Davidsson, OB., Kristjansson, RP., Thorleifsson, G., Helgadottir, A., Gretarsdottir, S., Norddahl, G., Rajamani, S., Torfason, B., Valgardsson, AS., Sverrisson, JT., Tragante, V., Holmen, OL., & 15 othersAsselbergs, FW., Roden, DM., Darbar, D., Pedersen, TR., Sabatine, MS., Willer, CJ., Løchen, ML., Halldorsson, BV., Jonsdottir, I., Hveem, K., Arnar, DO., Thorsteinsdottir, U., Gudbjartsson, DF., Holm, H. & Stefansson, K., 12 Jun 2018, In: Communications Biology. 1, 1, 68.

Research output: Contribution to journal › Article › Academic › peer-review

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Lin, H., van Setten, J., Smith, AV., Bihlmeyer, NA., Warren, HR., Brody, JA., Radmanesh, F., Hall, L., Grarup, N., Mueller-Nurasyid, M., Boutin, T., Verweij, N., Lin, HJ., Li-Gao, R., van den Berg, ME., Marten, J., Weiss, S., Prins, BP., Haessler, J., Lyytikainen, L-P., & 78 othersMei, H., Harris, TB., Launer, LJ., Li, M., Alonso, A., Soliman, EZ., Connell, JM., Huang, PL., Weng, L-C., Jameson, HS., Hucker, W., Hanley, A., Tucker, NR., Chen, Y-DI., Bis, JC., Rice, KM., Sitlani, CM., Kors, JA., Xie, Z., Wen, C., Magnani, JW., Nelson, CP., Kanters, JK., Sinner, MF., Strauch, K., Peters, A., Waldenberger, M., Meitinger, T., Bork-Jensen, J., Pedersen, O., Linneberg, A., Rudan, I., de Boer, RA., van der Meer, P., Yao, J., Guo, X., Taylor, KD., Sotoodehnia, N., Rotter, JI., Mook-Kanamori, DO., Trompet, S., Rivadeneira, F., Uitterlinden, A., Eijgelsheim, M., Padmanabhan, S., Smith, BH., Volzke, H., Mangino, M., Spector, TD., Bots, ML., Perez, M., Kahonen, M., Raitakari, OT., Gudnason, V., Arking, DE., Munroe, PB., Psaty, BM., van Duijn, CM., Benjamin, EJ., Rosand, J., Samani, NJ., Hansen, T., Kaeaeb, S., Polasek, O., van der Harst, P., Heckbert, SR., Jukema, JW., Stricker, BH., Hayward, C., Doerr, M., Jamshidi, Y., Asselbergs, FW., Kooperberg, C., Lehtimaki, T., Wilson, JG., Ellinor, PT., Lubitz, SA. & Isaacs, A., 1 May 2018, In: Circulation. Genomic and precision medicine. 11, 5

Research output: Contribution to journal › Article › Academic › peer-review

Correction: Myofilament Remodeling and Function Is More Impaired in Peripartum Cardiomyopathy Compared with Dilated Cardiomyopathy and Ischemic Heart Disease

Bollen, IAE., Ehler, E., Fleischanderl, K., Bouwman, F., Kempers, L., Ricke-Hoch, M., Hilfiker-Kleiner, D., Dos Remedios, CG., Kruger, M., Vink, A., Asselbergs, FW., van Spaendonck-Zwarts, KY., Pinto, YM., Kuster, DWD. & van der Velden, J., 1 Mar 2018, In: American journal of pathology. 188, 3, p. 828-829 2 p.

Research output: Contribution to journal › Article › Academic › peer-review

Dilated Cardiomyopathy Due to BLC2-Associated Athanogene 3 (BAG3) Mutations

European Genetic Cardiomyopathies Initiative Investigators, 13 Nov 2018, In: Journal of the American College of Cardiology. 72, 20, p. 2471-2481

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

85 Citations (Scopus)

Druggability of Coronary Artery Disease Risk Loci

Tragante, V., Hemerich, D., Alshabeeb, M., Braenne, I., Lempiaeinen, H., Patel, RS., den Ruijter, HM., Barnes, MR., Moore, JH., Schunkert, H., Erdmann, J. & Asselbergs, FW., 1 Aug 2018, In: Circulation. Genomic and precision medicine. 11, 8

Research output: Contribution to journal › Article › Academic › peer-review

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Prins, BP., Mead, TJ., Brody, JA., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, NA., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, NT., Gabriel, GC., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, LM., Iorio, A., Isaacs, A., Li-Gao, R., & 93 othersLin, H., Liu, C-T., Lyytikainen, L-P., Marten, J., Mei, H., Mueller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, AV., Verweij, N., Warren, HR., Weiss, S., Alonso, A., Arnar, DO., Bots, ML., de Boer, RA., Dominiczak, AF., Eijgelsheim, M., Ellinor, PT., Guo, X., Felix, SB., Harris, TB., Hayward, C., Heckbert, SR., Huang, PL., Jukema, JW., Kahonen, M., Kors, JA., Lambiase, PD., Launer, LJ., Li, M., Linneberg, A., Nelson, CP., Pedersen, O., Perez, M., Peters, A., Polasek, O., Psaty, BM., Raitakari, OT., Rice, KM., Rotter, JI., Sinner, MF., Soliman, EZ., Spector, TD., Strauch, K., Thorsteinsdottir, U., Tinker, A., Trompet, S., Uitterlinden, A., Vaartjes, I., van der Meer, P., Voelker, U., Voelzke, H., Waldenberger, M., Wilson, JG., Xie, Z., Asselbergs, FW., Doerr, M., van Duijn, CM., Gasparini, P., Gudbjartsson, DF., Gudnason, V., Hansen, T., Kaeaeb, S., Kanters, JK., Kooperberg, C., Lehtimaki, T., Lin, HJ., Lubitz, SA., Mook-Kanamori, DO., Conti, FJ., Newton-Cheh, CH., Rosand, J., Rudan, I., Samani, NJ., Sinagra, G., Smith, BH., Holm, H., Stricker, BH., Ulivi, S., Sotoodehnia, N., Apte, SS., van der Harst, P., Stefansson, K., Munroe, PB., Arking, DE., Lo, CW. & Jamshidi, Y., 17 Jul 2018, In: Genome Biology. 19, ARTN 87

Research output: Contribution to journal › Article › Academic › peer-review

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Bihlmeyer, NA., Brody, JA., Smith, AV., Warren, HR., Lin, H., Isaacs, A., Liu, C-T., Marten, J., Radmanesh, F., Hall, LM., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, JE., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S., & 80 othersPrins, BP., van Setten, J., Haessler, J., Lyytikainen, L-P., Li, M., Alonso, A., Soliman, EZ., Bis, JC., Austin, T., Chen, Y-DI., Psaty, BM., Harrris, TB., Launer, LJ., Padmanabhan, S., Dominiczak, A., Huang, PL., Xie, Z., Ellinor, PT., Kors, JA., Campbell, A., Murray, AD., Nelson, CP., Tobin, MD., Bork-Jensen, J., Hansen, T., Pedersen, O., Linneberg, A., Sinner, MF., Peters, A., Waldenberger, M., Meitinger, T., Perz, S., Kolcic, I., Rudan, I., de Boer, RA., van der Meer, P., Lin, HJ., Taylor, KD., de Mutsert, R., Trompet, S., Jukema, JW., Maan, AC., Stricker, BHC., Rivadeneira, F., Uitterlinden, A., Volker, U., Homuth, G., Volzke, H., Felix, SB., Mangino, M., Spector, TD., Bots, ML., Perez, M., Raitakari, OT., Kahonen, M., Mononen, N., Gudnason, V., Munroe, PB., Lubitz, SA., van Duijn, CM., Newton-Cheh, CH., Hayward, C., Rosand, J., Samani, NJ., Kanters, JK., Wilson, JG., Kaab, S., Polasek, O., van der Harst, P., Heckbert, SR., Rotter, JI., Mook-Kanamori, DO., Eij-Gelsheim, M., Dorr, M., Jamshidi, Y., Asselbergs, FW., Kooperberg, C., Lehtimaki, T., Arking, DE. & Sotoodehnia, N., 1 Jan 2018, In: Circulation: Genomic and Precision Medicine. 11, 1

Research output: Contribution to journal › Article › Academic › peer-review

From lipid locus to drug target through human genomics

van der Laan, SW., Harshfield, EL., Hemerich, D., Stacey, D., Wood, AM. & Asselbergs, FW., 15 Jul 2018, In: Cardiovascular research. 114, 9, p. 1258-1270 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

van der Laan, SW., Siemelink, MA., Haitjema, S., Asl, HF., Perisic, L., Mokry, M., van Setten, J., Malik, R., Dichgans, M., Worrall, BB., Samani, NJ., Schunkert, H., Erdmann, J., Hedin, U., Paulsson-Berne, G., Bjorkegrenn, JLM., de Borst, GJ., Asselbergs, FW., den Ruijter, HM., de Bakker, PIW., & 1 othersPasterkamp, G., 17 Sept 2018, In: Circulation. Genomic and precision medicine. 11, 9

Research output: Contribution to journal › Article › Academic › peer-review

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

Gudmundsson, J., Sigurdsson, J. K., Stefansdottir, L., Agnarsson, B. A., Isaksson, H. J., Stefansson, O. A., Gudjonsson, S. A., Gudbjartsson, D. F., Masson, G., Frigge, M. L., Stacey, S. N., Sulem, P., Halldorsson, G. H., Tragante, V., Holm, H., Eyjolfsson, G. I., Sigurdardottir, O., Olafsson, I., Jonsson, T., Jonsson, E., & 8 othersBarkardottir, R. B., Hilmarsson, R., Asselbergs, F. W., Geirsson, G., Thorsteinsdottir, U., Rafnar, T., Thorleifsson, G. & Stefansson, K., 1 Dec 2018, In: Nature communications. 9, 1, 4568.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

32 Citations (Scopus)

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets

Lempiäinen, H., Brænne, I., Michoel, T., Tragante, V., Vilne, B., Webb, T. R., Kyriakou, T., Eichner, J., Zeng, L., Willenborg, C., Franzen, O., Ruusalepp, A., Goel, A., van der Laan, S. W., Biegert, C., Hamby, S., Talukdar, H. A., Foroughi Asl, H., Dichgans, M., Dreker, T., & 15 othersGraettinger, M., Gribbon, P., Kessler, T., Malik, R., Prestel, M., Stiller, B., Schofield, C., Pasterkamp, G., Watkins, H., Samani, N. J., Wittenberger, T., Erdmann, J., Schunkert, H., Asselbergs, F. W. & Björkegren, J. L. M., 1 Dec 2018, In: Scientific reports. 8, 1, 3434.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

40 Citations (Scopus)

Plasminogen activator inhibitor-1 and tissue plasminogen activator and incident AF: Data from the PREVEND study

Mulder, B. A., Geelhoed, B., van der Harst, P., Spronk, HM., Van Gelder, IC., Asselbergs, FW. & Rienstra, M., 10 Aug 2018, In: International journal of cardiology. 272, p. 208-210

Research output: Contribution to journal › Article › Academic › peer-review

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikäinen, L-P., Müller, C., Müller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., Smith, A. V., & 106 othersSteri, M., Tanaka, T., Teumer, A., Trompet, S., Ulivi, S., Verweij, N., Yin, X., Arnar, D. O., Asselbergs, F. W., Bader, J. S., Barnard, J., Bis, J., Blankenberg, S., Boerwinkle, E., Bradford, Y., Buckley, B. M., Chung, M. K., Crawford, D., den Hoed, M., Denny, J. C., Dominiczak, A. F., Ehret, G. B., Eijgelsheim, M., Ellinor, P. T., Felix, S. B., Franco, O. H., Franke, L., Harris, T. B., Holm, H., Ilaria, G., Iorio, A., Kähönen, M., Kolcic, I., Kors, J. A., Lakatta, E. G., Launer, L. J., Lin, H., Lin, H. J., Loos, R. J. F., Lubitz, S. A., Macfarlane, P. W., Magnani, J. W., Leach, I. M., Meitinger, T., Mitchell, B. D., Munzel, T., Papanicolaou, G. J., Peters, A., Pfeufer, A., Pramstaller, P. P., Raitakari, O. T., Rotter, J. I., Rudan, I., Samani, N. J., Schlessinger, D., Silva Aldana, C. T., Sinner, M. F., Smith, J. D., Snieder, H., Soliman, E. Z., Spector, T. D., Stott, D. J., Strauch, K., Tarasov, K. V., Thorsteinsdottir, U., Uitterlinden, A. G., van Wagoner, D. R., Völker, U., Völzke, H., Waldenberger, M., Jan Westra, H., Wild, P. S., Zeller, T., Alonso, A., Avery, C. L., Bandinelli, S., Benjamin, E. J., Cucca, F., Dörr, M., Ferrucci, L., Gasparini, P., Gudnason, V., Hayward, C., Heckbert, S. R., Hicks, A. A., Jukema, J. W., Kääb, S., Lehtimäki, T., Liu, Y., Munroe, P. B., Parsa, A., Polasek, O., Psaty, B. M., Roden, D. M., Schnabel, R. B., Sinagra, G., Stefansson, K., Stricker, B. H., van der Harst, P., van Duijn, C. M., Wilson, J. F., Gharib, S. A., de Bakker, P. I. W., Isaacs, A., Arking, D. E. & Sotoodehnia, N., 1 Dec 2018, In: Nature communications. 9, 1, 2904.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

62 Citations (Scopus)

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2018)

Turcot, V., Lu, Y., Highland, HM., Schurmann, C., Justice, AE., Fine, RS., Bradfield, JP., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, AE., Karaderi, T., Lempradl, A., Locke, AE., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, KL., Alfred, T., & 381 othersFeitosa, MF., Masca, NGD., Manning, AK., Medina-Gomez, C., Mudgal, P., Ng, MCY., Reiner, AP., Vedantam, S., Willems, SM., Winkler, TW., Abecasis, G., Aben, KK., Alam, DS., Alharthi, SE., Allison, M., Amouyel, P., Asselbergs, FW., Auer, PL., Balkau, B., Bang, LE., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, LF., Bluher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Boger, CA., Bork-Jensen, J., Bots, ML., Bottinger, EP., Bowden, DW., Brandslund, I., Breen, G., Brilliant, MH., Broer, L., Brumat, M., Burt, AA., Butterworth, AS., Campbell, PT., Cappellani, S., Carey, DJ., Catamo, E., Caulfield, MJ., Chambers, JC., Chasman, DI., Chen, Y-DI., Chowdhury, R., Christensen, C., Chu, AY., Cocca, M., Collins, FS., Cook, JP., Corley, J., Galbany, JC., Cox, AJ., Crosslin, DS., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, PIW., Groot, MCH., Mutsert, R., Deary, IJ., Dedoussis, G., Demerath, EW., Heijer, M., Hollander, AI., Ruijter, HM., Dennis, JG., Denny, JC., Di Angelantonio, E., Drenos, F., Du, M., Dube, M-P., Dunning, AM., Easton, DF., Edwards, TL., Ellinghaus, D., Ellinor, PT., Elliott, P., Evangelou, E., Farmaki, A-E., Farooqi, IS., Faul, JD., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, JC., Ford, I., Fornage, M., Franco, OH., Franke, A., Franks, PW., Friedrich, N., Frikke-Schmidt, R., Galesloot, TE., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, AP., Gordon-Larsen, P., Gorski, M., Grabe, H-J., Grant, SFA., Grarup, N., Griffiths, HL., Grove, ML., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, AR., Hansen, T., Harris, KM., Harris, TB., Hattersley, AT., Have, CT., Hayward, C., He, L., Heard-Costa, NL., Heath, AC., Heid, IM., Helgeland, O., Hernesniemi, J., Hewitt, AW., Holmen, OL., Hovingh, GK., Howson, JMM., Hu, Y., Huang, PL., Huffman, JE., Ikram, MA., Ingelsson, E., Jackson, AU., Jansson, J-H., Jarvik, GP., Jensen, GB., Jia, Y., Johansson, S., Jorgensen, ME., Jorgensen, T., Jukema, JW., Kahali, B., Kahn, RS., Kahonen, M., Kamstrup, PR., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, SLR., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, LA., Kim, E., Kitajima, H., Komulainen, P., Kooner, JS., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, TA., Lamparter, D., Lange, EM., Lange, LA., Langenberg, C., Larson, EB., Lee, NR., Lehtimaki, T., Lewis, CE., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K-H., Lin, L-A., Lin, X., Lind, L., Lindstrom, J., Linneberg, A., Liu, C-T., Liu, DJ., Liu, Y., Lo, KS., Lophatananon, A., Lotery, AJ., Loukola, A., Luan, J., Lubitz, SA., Lyytikainen, L-P., Mannisto, S., Marenne, G., Mazul, AL., McCarthy, MI., McKean-Cowdin, R., Medland, SE., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, KL., Moilanen, L., Moitry, M., Montgomery, GW., Mook-Kanamori, DO., Moore, C., Mori, TA., Morris, AD., Morris, AP., Mueller-Nurasyid, M., Munroe, PB., Nalls, MA., Narisu, N., Nelson, CP., Neville, M., Nielsen, SF., Nikus, K., Njolstad, PR., Nordestgaard, BG., Nyholt, DR., O'Connel, JR., O'Donoghue, ML., Loohuis, LMO., Ophoff, RA., Owen, KR., Packard, CJ., Padmanabhan, S., Palmer, CNA., Palmer, ND., Pasterkamp, G., Patel, AP., Pattie, A., Pedersen, O., Peissig, PL., Peloso, GM., Pennell, CE., Perola, M., Perry, JA., Perry, JRB., Pers, TH., Person, TN., Peters, A., Petersen, ERB., Peyser, PA., Pirie, A., Polasek, O., Polderman, TJ., Puolijoki, H., Raitakari, OT., Rasheed, A., Rauramaa, R., Reilly, DF., Renstrom, F., Rheinberger, M., Ridker, PM., Rioux, JD., Rivas, MA., Roberts, DJ., Robertson, NR., Robino, A., Rolandsson, O., Rudan, I., Ruth, KS., Saleheen, D., Salomaa, V., Samani, NJ., Sapkota, Y., Sattar, N., Schoen, RE., Schreiner, PJ., Schulze, MB., Scott, RA., Segura-Lepe, MP., Shah, SH., Sheu, WH-H., Sim, X., Slater, AJ., Small, KS., Smith, AV., Southam, L., Spector, TD., Speliotes, EK., Starr, JM., Stefansson, K., Steinthorsdottir, V., Stirrups, KE., Strauch, K., Stringham, HM., Stumvoll, M., Sun, L., Surendran, P., Swift, AJ., Tada, H., Tansey, KE., Tardif, J-C., Taylor, KD., Teumer, A., Thompson, DJ., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, BH., Tonjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, JP., Uher, R., Uitterlinden, AG., Uusitupa, M., Laan, SW., Duijn, CM., Leeuwen, N., van Setten, J., Vanhala, M., Varbo, A., Varga, TV., Varma, R., Edwards, DRV., Vermeulen, SH., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, TF., Volker, U., Vuckovic, D., Wagenknecht, LE., Walker, M., Wallentin, L., Wang, F., Wang, CA., Wang, S., Wang, Y., Ware, EB., Wareham, NJ., Warren, HR., Waterworth, DM., Wessel, J., White, HD., Willer, CJ., Wilson, JG., Witte, DR., Wood, AR., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, LM., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, JH., Zhao, W., Zhou, W., Zondervan, KT., Consortium, GG., Rotter, JI., Pospisilik, JA., Rivadeneira, F., Borecki, IB., Deloukas, P., Frayling, TM., Lettre, G., North, KE., Lindgren, CM., Hirschhorn, JN. & Loos, RJF., 16 Mar 2018, In: Nature Genetics. 50, 5, p. 766-767 2 p.

Research output: Contribution to journal › Article › Academic › peer-review

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 765, 2017)

Turcot, V., Lu, Y., Highland, HM., Schurmann, C., Justice, AE., Fine, RS., Bradfield, JP., Esko, T., Giri, A., Graff, M., Guo, X., Hendricks, AE., Karaderi, T., Lempradl, A., Locke, AE., Mahajan, A., Marouli, E., Sivapalaratnam, S., Young, KL., Alfred, T., & 380 othersFeitosa, MF., Masca, NGD., Manning, AK., Medina-Gomez, C., Mudgal, P., Ng, MCY., Reiner, AP., Vedantam, S., Willems, SM., Winkler, TW., Abecasis, G., Aben, KK., Alam, DS., Alharthi, SE., Allison, M., Amouyel, P., Asselbergs, FW., Auer, PL., Balkau, B., Bang, LE., Barroso, I., Bastarache, L., Benn, M., Bergmann, S., Bielak, LF., Bluher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Boger, CA., Bork-Jensen, J., Bots, ML., Bottinger, EP., Bowden, DW., Brandslund, I., Breen, G., Brilliant, MH., Broer, L., Brumat, M., Burt, AA., Butterworth, AS., Campbell, PT., Cappellani, S., Carey, DJ., Catamo, E., Caulfield, MJ., Chambers, JC., Chasman, DI., Chen, Y-DI., Chowdhury, R., Christensen, C., Chu, AY., Cocca, M., Collins, FS., Cook, JP., Corley, J., Galbany, JC., Cox, AJ., Crosslin, DS., Cuellar-Partida, G., D'Eustacchio, A., Danesh, J., Davies, G., Bakker, PIW., Groot, MCH., Mutsert, R., Deary, IJ., Dedoussis, G., Demerath, EW., Heijer, M., Hollander, AI., Ruijter, HM., Dennis, JG., Denny, JC., Angelantonio, E., Drenos, F., Du, M., Dube, M-P., Dunning, AM., Easton, DF., Edwards, TL., Ellinghaus, D., Ellinor, PT., Elliott, P., Evangelou, E., Farmaki, A-E., Farooqi, IS., Faul, JD., Fauser, S., Feng, S., Ferrannini, E., Ferrieres, J., Florez, JC., Ford, I., Fornage, M., Franco, OH., Franke, A., Franks, PW., Friedrich, N., Frikke-Schmidt, R., Galesloot, TE., Gan, W., Gandin, I., Gasparini, P., Gibson, J., Giedraitis, V., Gjesing, AP., Gordon-Larsen, P., Gorski, M., Grabe, H-J., Grant, SFA., Grarup, N., Griffiths, HL., Grove, ML., Gudnason, V., Gustafsson, S., Haessler, J., Hakonarson, H., Hammerschlag, AR., Hansen, T., Harris, KM., Harris, TB., Hattersley, AT., Have, CT., Hayward, C., He, L., Heard-Costa, NL., Heath, AC., Heid, IM., Helgeland, O., Hernesniemi, J., Hewitt, AW., Holmen, OL., Hovingh, GK., Howson, JMM., Hu, Y., Huang, PL., Huffman, JE., Ikram, MA., Ingelsson, E., Jackson, AU., Jansson, J-H., Jarvik, GP., Jensen, GB., Jia, Y., Johansson, S., Jorgensen, ME., Jorgensen, T., Jukema, JW., Kahali, B., Kahn, RS., Kahonen, M., Kamstrup, PR., Kanoni, S., Kaprio, J., Karaleftheri, M., Kardia, SLR., Karpe, F., Kathiresan, S., Kee, F., Kiemeney, LA., Kim, E., Kitajima, H., Komulainen, P., Kooner, JS., Kooperberg, C., Korhonen, T., Kovacs, P., Kuivaniemi, H., Kutalik, Z., Kuulasmaa, K., Kuusisto, J., Laakso, M., Lakka, TA., Lamparter, D., Lange, EM., Lange, LA., Langenberg, C., Larson, EB., Lee, NR., Lehtimaki, T., Lewis, CE., Li, H., Li, J., Li-Gao, R., Lin, H., Lin, K-H., Lin, L-A., Lin, X., Lind, L., Lindstrom, J., Linneberg, A., Liu, C-T., Liu, DJ., Liu, Y., Lo, KS., Lophatananon, A., Lotery, AJ., Loukola, A., Luan, J., Lubitz, SA., Lyytikainen, L-P., Mannisto, S., Marenne, G., Mazul, AL., McCarthy, MI., McKean-Cowdin, R., Medland, SE., Meidtner, K., Milani, L., Mistry, V., Mitchell, P., Mohlke, KL., Moilanen, L., Moitry, M., Montgomery, GW., Mook-Kanamori, DO., Moore, C., Mori, TA., Morris, AD., Morris, AP., Mueller-Nurasyid, M., Munroe, PB., Nalls, MA., Narisu, N., Nelson, CP., Neville, M., Nielsen, SF., Nikus, K., Njolstad, PR., Nordestgaard, BG., Nyholt, DR., O'Connel, JR., O'Donoghue, ML., Loohuis, LMO., Ophoff, RA., Owen, KR., Packard, CJ., Padmanabhan, S., Palmer, CNA., Palmer, ND., Pasterkamp, G., Patel, AP., Pattie, A., Pedersen, O., Peissig, PL., Peloso, GM., Pennell, CE., Perola, M., Perry, JA., Perry, JRB., Pers, TH., Person, TN., Peters, A., Petersen, ERB., Peyser, PA., Pirie, A., Polasek, O., Polderman, TJ., Puolijoki, H., Raitakari, OT., Rasheed, A., Rauramaa, R., Reilly, DF., Renstrom, F., Rheinberger, M., Ridker, PM., Rioux, JD., Rivas, MA., Roberts, DJ., Robertson, NR., Robino, A., Rolandsson, O., Rudan, I., Ruth, KS., Saleheen, D., Salomaa, V., Samani, NJ., Sapkota, Y., Sattar, N., Schoen, RE., Schreiner, PJ., Schulze, MB., Scott, RA., Segura-Lepe, MP., Shah, SH., Sheu, WH-H., Sim, X., Slater, AJ., Small, KS., Smith, AV., Southam, L., Spector, TD., Speliotes, EK., Starr, JM., Stefansson, K., Steinthorsdottir, V., Stirrups, KE., Strauch, K., Stringham, HM., Stumvoll, M., Sun, L., Surendran, P., Swift, AJ., Tada, H., Tansey, KE., Tardif, J-C., Taylor, KD., Teumer, A., Thompson, DJ., Thorleifsson, G., Thorsteinsdottir, U., Thuesen, BH., Tonjes, A., Tromp, G., Trompet, S., Tsafantakis, E., Tuomilehto, J., Tybjaerg-Hansen, A., Tyrer, JP., Uher, R., Uitterlinden, AG., Uusitupa, M., Laan, SW., Duijn, CM., Leeuwen, N., van Setten, J., Vanhala, M., Varbo, A., Varga, TV., Varma, R., Edwards, DRV., Vermeulen, SH., Veronesi, G., Vestergaard, H., Vitart, V., Vogt, TF., Volker, U., Vuckovic, D., Wagenknecht, LE., Walker, M., Wallentin, L., Wang, F., Wang, CA., Wang, S., Wang, Y., Ware, EB., Wareham, NJ., Warren, HR., Waterworth, DM., Wessel, J., White, HD., Willer, CJ., Wilson, JG., Witte, DR., Wood, AR., Wu, Y., Yaghootkar, H., Yao, J., Yao, P., Yerges-Armstrong, LM., Young, R., Zeggini, E., Zhan, X., Zhang, W., Zhao, JH., Zhao, W., Zhou, W., Zondervan, KT., Rotter, JI., Pospisilik, JA., Rivadeneira, F., Borecki, IB., Deloukas, P., Frayling, TM., Lettre, G., North, KE., Lindgren, CM., Hirschhorn, JN. & Loos, RJF., 16 Mar 2018, In: Nature Genetics. 50, 5, p. 765-766 2 p.

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Routinely measured hematological parameters and prediction of recurrent vascular events in patients with clinically manifest vascular disease

Kofink, D., Muller, SA., Patel, RS., Dorresteijn, JAN., Berkelmans, GFN., De Groot, MCH., Van Solinge, WW., Haitjema, S., Leiner, T., Visseren, FLJ., Hoefer, IE. & Asselbergs, F. W., 1 Sept 2018, In: PLOS ONE. 13, 9

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Variable cardiac myosin binding protein-C expression in the myofilaments due to MYBPC3 mutations in hypertrophic cardiomyopathy

Parbhudayal, RY., Garra, AR., Götte, MJW., Michels, M., Pei, J., Harakalova, M., Asselbergs, FW., van Rossum, AC., van der Velden, J. & Kuster, DWD., 1 Oct 2018, In: Journal of molecular and cellular cardiology. 123, p. 59-63 5 p.

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Open Access

19 Citations (Scopus)

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits

Rafnar, T., Gunnarsson, B., Stefansson, OA., Sulem, P., Ingason, A., Frigge, ML., Stefansdottir, L., Sigurdsson, JK., Tragante, V., Steinthorsdottir, V., Styrkarsdottir, U., Stacey, SN., Gudmundsson, J., Arnadottir, GA., Oddsson, A., Zink, F., Halldorsson, G., Sveinbjornsson, G., Kristjansson, RP., Davidsson, OB., & 17 othersSalvarsdottir, A., Thoroddsen, A., Helgadottir, EA., Kristjansdottir, K., Ingthorsson, O., Gudmundsson, V., Geirsson, RT., Arnadottir, R., Gudbjartsson, DF., Masson, G., Asselbergs, FW., Jonasson, JG., Olafsson, K., Thorsteinsdottir, U., Halldorsson, BV., Thorleifsson, G. & Stefansson, K., 7 Sept 2018, In: Nature communications. 9, ARTN 3636, 9 p., 3636.

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Women-specific risk factors for heart failure: A genetic approach

van der Kemp, J., van der Schouw, YT., Asselbergs, FW. & Onland-Moret, NC., 1 Mar 2018, In: Maturitas. 109, p. 104-111 8 p.

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2019

A comparison of two workflows for regulome and transcriptome-based prioritization of genetic variants associated with myocardial mass

Manduchi, E., Hemerich, D., van Setten, J., Tragante, V., Harakalova, M., Pei, J., Williams, S. M., van der Harst, P., Asselbergs, F. W. & Moore, J. H., 2019, In: Genetic epidemiology. 43, 6, p. 717-726

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1 Citation (Scopus)

Adverse Drug Reactions to Guideline-Recommended Heart Failure Drugs in Women: A Systematic Review of the Literature

Bots, S. H., Groepenhoff, F., Eikendal, ALM., Tannenbaum, C., Rochon, PA., Regitz-Zagrosek, V., Miller, VM., Day, D., Asselbergs, FW. & den Ruijter, HM., 1 Mar 2019, In: JACC. Heart Failure. 7, 3, p. 258-266 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M., & 416 othersBaumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I. T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G. S., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H. H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., de Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O’connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E. S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T. N., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 1 Dec 2019, In: Nature communications. 10, 1, p. 1-17 17 p., 4957.

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54 Citations (Scopus)

Big data analytics in adult congenital heart disease: Why coding matters

Asselbergs, FW. & Meijboom, FJ., 1 Apr 2019, In: European Heart journal. 40, 13, p. 1078-1080 3 p.

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Cardiac amyloidosis: the need for early diagnosis

Oerlemans, MIFJ., Rutten, KHG., Minnema, MC., Raymakers, RAP., Asselbergs, FW. & de Jonge, N., 29 Jul 2019, In: Netherlands heart journal. 27, p. 525-536

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Details on high frequency blood collection, data analysis, available material and patient characteristics in BIOMArCS

Boersma, E., Vroegindewey, MM., van den Berg, VJ., Asselbergs, FW., van der Harst, P., Kietselaer, B., Lenderink, T., Oude Ophuis, AJ., Umans, VAWM., de Winter, R. J., Oemrawsingh, RM. & Akkerhuis, KM., 1 Dec 2019, In: Data in brief. 27, 104750.

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Discovery of biomarkers for the presence and progression of left ventricular diastolic dysfunction and HEart faiLure with Preserved ejection Fraction in patients at risk for cardiovascular disease: Rationale and design of the HELPFul case-cohort study in a Dutch cardiology outpatient clinic

Valstar, GB., Bots, SH., Groepenhoff, F., Gohar, A., Rutten, FH., Leiner, T., Cramer, MJM., Teske, AJ., Suciadi, LP., Menken, R., Pasterkamp, G., Asselbergs, FW., Hofstra, L., Bots, ML., Den Ruijter, HM., Bots, S. H. & Rutten, F. H., 5 Jun 2019, In: BMJ Open. 9, 6, e028408.

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Open Access

9 Citations (Scopus)

Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use

Nielsen, SF., de Craen, AJM., Reily, DF., Butterworth, AS., Howson, JMM., Jackson, VE., Varga, TV., Warren, HR., Tragante, V., Tachmazidou, I., Harris, SE., Evangelou, E., Marten, J., Zhang, W., Altmaier, E., Luan, J., Langenberg, C., Scott, RA., Yaghootkar, H., Stirrups, K., & 28 othersKanoni, S., Marouli, E., Karpe, F., Dominiczak, AF., Sever, P., Poulter, N., Rolandsson, O., Baumbach, C., Afaq, S., Chambers, JC., Kooner, JS., Wareham, NJ., Renström, F., Hallmans, G., Marioni, RE., Corley, J., Starr, JM., Verweij, N., de Boer, RA., van der Meer, P., Yavas, E., Vaartjes, I., Bots, ML., Asselbergs, FW., Grabe, HJ., Völzke, H., CHD Exome+ Consortium & Consortium for Genetics of Smoking Behaviour, 1 Jun 2019, In: Biological Psychiatry. 11, 11, p. 946-955 10 p.

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50 Citations (Scopus)

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

van Setten, J., Verweij, N., Mbarek, H., Niemeijer, M. N., Trompet, S., Arking, D. E., Brody, J. A., Gandin, I., Grarup, N., Hall, L. M., Hemerich, D., Lyytikäinen, L-P., Mei, H., Müller-Nurasyid, M., Prins, B. P., Robino, A., Smith, A. V., Warren, H. R., Asselbergs, F. W., Boomsma, D. I., & 41 othersCaulfield, M. J., Eijgelsheim, M., Ford, I., Hansen, T., Harris, T. B., Heckbert, S. R., Hottenga, J-J., Iorio, A., Kors, J. A., Linneberg, A., MacFarlane, P. W., Meitinger, T., Nelson, C. P., Raitakari, O. T., Silva Aldana, C. T., Sinagra, G., Sinner, M., Soliman, E. Z., Stoll, M., Uitterlinden, A., van Duijn, C. M., Waldenberger, M., Alonso, A., Gasparini, P., Gudnason, V., Jamshidi, Y., Kääb, S., Kanters, J. R. K., Lehtimäki, T., Munroe, P. B., Peters, A., Samani, N. J., Sotoodehnia, N., Ulivi, S., Wilson, J. G., de Geus, E. J. C., Jukema, J. W., Stricker, B., van der Harst, P., de Bakker, P. I. W. & Isaacs, A., 1 Jun 2019, In: European journal of human genetics. 27, 6, p. 952-962

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25 Citations (Scopus)

Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1

Pei, J., Juni, R., Harakalova, M., Duncker, DJ., Asselbergs, FW., Koolwijk, P., van Hinsbergh, V., Verhaar, MC., Mokry, M. & Cheng, C., 1 Aug 2019, In: TOXINS. 11, 8, p. 454 454.

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Open Access

12 Citations (Scopus)

Investigating the stratified efficacy and safety of pharmacological blood pressure-lowering: an overall protocol for individual patient-level data meta-analyses of over 300 000 randomised participants in the new phase of the Blood Pressure Lowering Treatment Trialists' Collaboration (BPLTTC)

Rahimi, K., Canoy, D., Nazarzadeh, M., Salimi-Khorshidi, G., Woodward, M., Teo, K., Davis, BR., Chalmers, J., Pepine, CJ., Rahimi, K., Teo, K., Davis, BR., Chalmers, J., Pepine, CJ., Agodoa, L., Algra, A., Asselbergs, FW., Beckett, N., Berge, E., Black, H., & 65 othersBrouwers, FPJ., Brown, M., Bulpitt, CJ., Byington, B., Chalmers, J., Cutler, J., Devereaux, RB., Dwyer, D., Fagard, R., Fox, K., Fukui, T., Gupta, AJ., Holman, RR., Imai, Y., Ishii, M., Julius, S., Kanno, Y., Kjeldsen, SE., Kostis, J., Kuramoto, K., Lanke, J., Lewis, E., Lievre, M., Lindholm, LH., Lueders, S., MacMahon, S., Matsuzaki, M., Mehlum, MH., Nissen, S., Ogawa, H., Othisgihara, T., Ohkubo, T., Palmer, C., Patel, A., Pepine, C., Pfeffer, M., Poulter, NR., Rakugi, H., Remuzzi, G., Ruggenenti, P., Saruta, T., Schrader, J., Schrier, R., Sever, P., Sleight, P., Staessen, JA., Suzuki, H., Thijs, L., Ueshima, K., Umemoto, S., van Gilst, WH., Verdecchia, P., Wachtell, K., Yui, Y., Yusuf, S., Baigent, C., Collins, R., de Zeeuw, D., Neal, B., Perkovic, V., Rahman, M., Remme, WJ., Rodgers, A., Sundstrom, J. & Turnbull, F., 1 Jul 2019, In: BMJ Open. 9, 5

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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Adnan, SD., Bots, ML., David, SP., de Boer, RA., Heath, A., Hsu, C., Iacono, WG., Kanoni, S., Kapoor, M., Kaprio, J., Kardia, SL., Karpe, F., Kontto, J., Kooner, JS., Kooperberg, C., Kuulasmaa, K., Laakso, M., Lai, D., Langenberg, C., Le, N., & 13 othersLettre, G., Loukola, A., Luan, J., Madden, PAF., Mangino, M., Marioni, RE., Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour, CHD Exome+ consortium, de Leeuw, C. A., Understanding Society Scientific Group, EPIC-CVD, GSCAN, Consortium for Genetics of Smoking Behaviour & CHD Exome+ Consortium, 7 Jan 2019, In: Molecular psychiatry. 25, 10, p. 2392-2409 18 p.

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70 Citations (Scopus)

Non-HLA genetic factors and their influence on heart transplant outcomes: A systematic review

Van Setten, J., Warmerdam, EG., Groot, OQ., De Jonge, N., Keating, B. & Asselbergs, FW., 1 Feb 2019, In: Transplantation direct. 5, 2

Research output: Contribution to journal › Article › Academic › peer-review

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

Lifelines Cohort authors, 29 Oct 2019, In: BMC Cardiovascular Disorders. 19, 1, 240.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

21 Citations (Scopus)

Progression of conventional cardiovascular risk factors and vascular disease risk in individuals: insights from the PROG-IMT consortium

Bahls, M., Lorenz, MW., Doerr, M., Gao, L., Kitagawa, K., Tuomainen, T-P., Agewall, S., Berenson, G., Catapano, AL., Norata, GD., Bots, ML., van Gilst, W., Asselbergs, FW., Brouwers, FP., Uthoff, H., Sander, D., Poppert, H., Olsen, MH., Empana, JP., Schminke, U., & 35 othersBaldassarre, D., Veglia, F., Franco, OH., Kavousi, M., de Groot, E., Mathiesen, EB., Grigore, L., Polak, JF., Rundek, T., Stehouwer, CDA., Skilton, MR., Hatzitolios, A., Savopoulos, C., Ntaios, G., Plichart, M., McLachlan, S., Lind, L., Willeit, P., Steinmetz, H., Desvarieux, M., Ikram, MA., Johnsen, SH., Schmidt, C., Willeit, J., Ducimetiere, P., Price, JF., Bergstrom, G., Kauhanen, J., Kiechl, S., Sitzer, M., Bickel, H., Sacco, RL., Hofman, A., Voelzke, H. & Thompson, SG., 16 Oct 2019, In: European journal of preventive cardiology. UNSP 2047487319877078

Research output: Contribution to journal › Article › Academic › peer-review

Risk factors for incident heart failure in age- and sex-specific strata: a population-based cohort using linked electronic health records

Uijl, A., Koudstaal, S., Direk, K., Denaxas, S., Groenwold, RHH., Banerjee, A., Hoes, AW., Hemingway, H. & Asselbergs, FW., 7 Jan 2019, In: European journal of heart failure.

Research output: Contribution to journal › Article › Academic › peer-review

Risk for Heart Failure: The Opportunity for Prevention With the American Heart Association's Life's Simple 7

Uijl, A., Koudstaal, S., Vaartjes, I., Boer, JMA., Verschuren, WMM., van der Schouw, YT., Asselbergs, FW., Hoes, AW. & Sluijs, I., 1 Aug 2019, In: JACC. Heart Failure. 7, 8, p. 637-647 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Targeted next-generation sequencing in Slovak cardiomyopathy patients

Nagyova, E., Radvanszky, J., Hyblova, M., Simovicova, V., Goncalvesova, E., Asselbergs, FW., Kadasi, L., Szemes, T. & Minarik, G., 1 Jan 2019, In: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY. 120, 1, p. 46-51 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

Temporal evolution of myeloperoxidase and galectin 3 during 1 year after acute coronary syndrome admission

Vroegindewey, MM., van den Berg, VJ., Bouwens, E., Akkerhuis, KM., Oemrawsingh, RM., Asselbergs, FW., Lenderink, T., van der Harst, P., Ronner, E., Umans, VAWM., Kardys, I. & Boersma, E., 1 Oct 2019, In: American Heart Journal. 216, p. 143-146 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

The temporal pattern of immune and inflammatory proteins prior to a recurrent coronary event in post-acute coronary syndrome patients

Vroegindewey, M. M., Oemrawsingh, R. M., Kardys, I., Asselbergs, F. W., van der Harst, P., Oude Ophuis, A. J., Etienne Cramer, G., Maas, A., Hong Kie The, S., Wardeh, A. J., Mouthaan, H., Boersma, E. & Akkerhuis, K. M., 17 Feb 2019, In: Biomarkers. 24, 2, p. 199-205

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

3 Citations (Scopus)

The Translational Landscape of the Human Heart

van Heesch, S., Witte, F., Schneider-Lunitz, V., Schulz, JF., Adami, E., Faber, AB., Kirchner, M., Maatz, H., Blachut, S., Sandmann, CL., Kanda, M., Worth, CL., Schafer, S., Calviello, L., Merriott, R., Patone, G., Hummel, O., Wyler, E., Obermayer, B., Mücke, MB., & 36 othersLindberg, EL., Trnka, F., Memczak, S., Schilling, M., Felkin, LE., Barton, PJR., Quaife, NM., Vanezis, K., Diecke, S., Mukai, M., Mah, N., Oh, SJ., Kurtz, A., Schramm, C., Schwinge, D., Sebode, M., Harakalova, M., Asselbergs, FW., Vink, A., de Weger, RA., Viswanathan, S., Widjaja, AA., Gärtner-Rommel, A., Milting, H., dos Remedios, C., Knosalla, C., Mertins, P., Landthaler, M., Vingron, M., Linke, WA., Seidman, JG., Seidman, CE., Rajewsky, N., Ohler, U., Cook, SA. & Hubner, N., 27 Jun 2019, In: Cell. 178, 1, p. 242-260.e29

Research output: Contribution to journal › Article › Academic › peer-review

UNRAVEL: big data analytics research data platform to improve care of patients with cardiomyopathies using routine electronic health records and standardised biobanking

Sammani, A., Jansen, M., Linschoten, M., Bagheri, A., de Jonge, N., Kirkels, H., van Laake, LW., Vink, A., van Tintelen, JP., Dooijes, D., te Riele, ASJM., Harakalova, M., Baas, AF. & Asselbergs, FW., 1 Sept 2019, In: Netherlands heart journal. 27, 9, p. 426-434 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Use of Pharmacogenetic Drugs by the Dutch Population

Alshabeeb, MA., Deneera, VHM., Khan, A. & Asselbergs, FW., 2 Jul 2019, In: Frontiers in genetics. 10, ARTN 567

Research output: Contribution to journal › Article › Academic › peer-review

2020

Age at menarche and heart failure risk: The EPIC-NL study

Plompen, M. V. L., van der Schouw, Y. T., Rutten, F. H., Verschuren, W. M. M., Boer, J. M. A., Asselbergs, F. W. & Onland-Moret, N. C., 1 Jan 2020, In: Maturitas. 131, p. 34-39

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

4 Citations (Scopus)

A registry-based algorithm to predict ejection fraction in patients with heart failure

Uijl, A., Lund, LH., Vaartjes, I., Brugts, JJ., Linssen, GC., Asselbergs, FW., Hoes, AW., Dahlstrom, U., Koudstaal, S. & Savarese, G., 17 Jun 2020, In: ESC heart failure. 7, 5, p. 2388 2397 p.

Research output: Contribution to journal › Article › Academic › peer-review

Bedside testing of CYP2C19 gene for treatment of patients with PCI with antiplatelet therapy

Al-Rubaish, AM., Al-Muhanna, FA., Alshehri, AM., Al-Mansori, MA., Alali, RA., Khalil, RM., Al Faraidy, KA., Cyrus, C., Sulieman, MM., Vatte, C., Claassens, DMF., Ten Berg, JM., Asselbergs, FW. & Al-Ali, AK., 3 Jun 2020, In: BMC Cardiovascular Disorders. 20, 1, p. 268-268 1 p.

Research output: Contribution to journal › Article › Academic › peer-review

Big data and artificial intelligence: Opportunities and threats in electrophysiology

van de Leur, R. R., Boonstra, M. J., Bagheri, A., Roudijk, R. W., Sammani, A., Taha, K., Doevendans, P. A. F. M., van der Harst, P., van Dam, P. M., Hassink, R. J., van Es, R. & Asselbergs, F. W., Nov 2020, In: Arrhythmia and Electrophysiology Review. 9, 3, p. 146-154 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

17 Citations (Scopus)

Open Access

44 Citations (Scopus)

Early- and late anthracycline-induced cardiac dysfunction: echocardiographic characterization and response to heart failure therapy

Kamphuis, J. A. M., Linschoten, M., Cramer, M. J., Doevendans, P. A., Asselbergs, F. W. & Teske, A. J., 2020, In: Cardio-oncology (London, England). 6, p. 23

Research output: Contribution to journal › Article › Academic › peer-review

Folkert Asselbergs

Research output

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