Ingeborg Klaassen

(Principal Investigator), PhD

1997 …2024

Research activity per year

Personal profile

Research interests

Short Biosketch PI:

Ingeborg Klaassen was trained  as a molecular/medical biologist at the University of Groningen and obtained her doctoral degree at the VU University Medical Center Amsterdam (PhD 2001).  She is Assistant Professor in the Department of Ophthalmology at Amsterdam UMC location University of Amsterdam since 2012. She is co-principal investigator together with prof. Reinier Schlingemann (ophthalmologist) of the Ocular Angiogenesis group


Research Interests:

  • Molecular mechanisms in retinal vascular disease, including diabetic retinopathy and age-related macular degeneration.
  • Special interest in the blood-retinal barrier, blood-brain barrier and microvascular permeability.
  • Molecular regulation of angiogenic tip cells/angiogenesis.
  • Retinal and cognitive dysfunction in type 2 diabetes
  • Vascular in vitro and in vivo models, including iPSC-derived vascular organoids
  • Biomarkers and patient-specific multi-omics approaches 



  • In vitro (co-)culture models of vascular permeability and angiogenesis
  • Developing mouse retina as a model for vascular sprouting and tip cell formation
  • Oxygen-induced retinopathy model as a model for pathological angiogenesis
  • Patient-specific multi-omics approaches

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

PhD, Determinants of Retinoid Sensitivity in Head and Neck Squamous Cell Carcinoma, Amsterdam UMC - Vrije Universiteit Amsterdam

Award Date: 15 Oct 2001

External positions

Board member, Nederlands Oogheelkundig Genootschap (NOG)

1 Feb 2023 → …

Board member, The Netherlands Association for Research in Vision and Ophthalmology (ARVO-NED)

1 Apr 2022 → …

Vice president, European Association for Diabetic Eye Complications

1 Sept 2021 → …

Collaborations and top research areas from the last five years

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