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Jan Willem Bruggeman

20182020

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Personal profile

Specialisation

Reproduction & Development

Research interests

Our soma is destined to perish eventually. Only our germ cells have the potential to replicate our genome "indefinitely", and pass it on to future generations. A somatic cell that acquires this potential is called a cancer cell. Indeed Jan Willem Bruggeman and colleagues found that tumors express hundreds of genes that are usually only found in developing germ cells. Because germ cell specific genes do not express in healthy somatic cells, this study provides handles for developing anticancer therapies with limited side effects. Our next step is to find out how these germ cell genes contribute to cancer development.

Jan Willem Bruggeman is a MD/PhD candidate at the fertility laboratory with dr. Geert Hamer and prof. dr. Ans van Pelt.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Network

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