Stalpers L.J.A.: Experimental radiotherapy: Effects and side-effects of irradiation

  • Bennis, Mick (Internal PhD candidate)
  • de Boer, Peter (Internal PhD candidate)
  • van Leeuwen, Caspar (Internal PhD candidate)
  • Oei, Arlene (Internal PhD candidate)
  • Stalpers, Lukas (Principal investigator)
  • Narayan, Ravi S. (External PhD candidate)

Project Details

Description

Ongoing projects (update 17 Sep 2016)

Vanderes project ; AMC METC 03/147 Assessment of aberrations in Premature Condensed Chromosomes (PCC) in cervical carcinomas after radiotherapy with cisplatin or hyperthermia. Principal investigators: Dr. Klaas Franken, dr. Lukas Stalpers en dr. Marrije Buist.
This project (together with project KWF UvA 2005-3228) was awarded 2012, Feb 13. with the Cozarelli-prize of the USA National Academy of Sciences for a 2011 PNAS paper of outstanding excellence and originality http://www.pnas.org/site/misc/cozzarelliprize.shtml (see Krawzcyk et al., 2011)

KWF-project UvA 2008-4019: Investigation of a gene set classifier for late radiation toxicity in prostate cancer patients. Principal investigators: dr. Klaas Franken AMC-UvA, dr. Harry Vrieling, LUMC, and dr. Lukas Stalpers, AMC. PhD-students: ir. Bregje van OOrschot.

KWF-project VU 2010-4874. Targeting resistance to radio-chemotherapy by inhibition of the PI3Kinase-Akt signalling pathway. Principal investigators: dr. Peter Sminia, VUmc, dr. Lukas Stalpers, AMC, and dr. Brigitta Baumert, MUMC-Maastro. PhD-student: drs. Ravi Narayan

KWF project UVA 2011- 5393: Active hot spot suppression to improve thermal dose and clinical outcome of locoregional hyperthermia treatment. Project leaders dr. J. (Hans) Crezee, dr. Petra Kok, dr. Lukas J.A. Stalpers. Post-doc: dr. Petra Kok

KWF project UVA 2012-5540: Towards biological treatment planning in radiotherapy combined with hyperthermia to improve clinical outcome. Project leaders: dr. Petra Kok, Dr. N. (Klaas) A.P. Franken, dr. Lukas J.A. Stalpers. PhD-students: drs. Caspar van Leeuwen, drs. Arlene Oei.

CCMO #39945, AMC METC 2012-104 (internal funding): The MPAC-study: a pilot for correlation of MRI diagnostic imaging and PAthological imaging of primary tumor extension in patients with cervix tumors. (Co)promotores: prof. Coen Rasch, prof. Gemma Kenter, dr. Lukas Stalpers. PhD-student: Peter de Boer, AGIKO.

KWF-project UVA 2014-7179. MRI based hyperthermia treatment planning. Principal investigators: dr. J. (Hans) Crezee, dr. Astrid van Lier (UMCU), dr. Lukas J.A. Stalpers. PhD-student: Mick Bennis, Soraya Gavazzi. Grant: € 572.500,-

KWF-project UvA 2015-7820: Sensitization of radiotherapy and cisplatin of cervical cancer by combined PARP1-inhibition and hyperthermia (PIs: N. Franken, L. Stalpers, J. Crezee) € 485.000,-
StatusActive
Effective start/end date1/07/2010 → …